Results 51 to 60 of about 2,979,616 (246)

A consistent molecular hydrogen isotope chemistry scheme based on an independent bond approximation [PDF]

, 2009
The isotopic composition of molecular hydrogen (H₂) produced by photochemical oxidation of methane (CH₄) and Volatile Organic Compounds (VOCs) is a key quantity in the global isotope budget of (H<sub>2 ...
Sub Atmospheric physics and chemistry, M. C. Krol, G. Pieterse, T. Röckmann, Krol, M.C., Pieterse, G., Afd Marine and Atmospheric Research, Marine and Atmospheric Research, Röckmann, T.   +8 more
core   +3 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Do atmospheric aerosols form glasses? [PDF]

, 2008
Zobrist B, Marcolli C, Pedernera DA, Koop T. Do atmospheric aerosols form glasses? ATMOSPHERIC CHEMISTRY AND PHYSICS. 2008;8(17):5221-5244.A new process is presented by which water soluble organics might influence ice nucleation, ice growth, chemical ...
Koop, Thomas, B. Zobrist, D. A. Pedernera, Koop, T., Koop, Thomas ; https://orcid.org/, Pedernera, D. A., Marcolli, C., C. Marcolli, T. Koop, Marcolli, Claudia, Pedernera, D.A., Zobrist, Bernhard, Zobrist, B.   +12 more
core   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Lidar-based minute-scale offshore wind speed forecasts analysed under different atmospheric conditions

Meteorologische Zeitschrift, 2022
In recent years, the potential of remote sensing-based minute-scale forecasts to improve the integration of wind power into our energy system has been shown.
Frauke Theuer, Marijn Floris van Dooren, Lueder von Bremen, Martin Kühn   +3 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Study on Vertical Extrapolation Model of Wind Speed in Inland Complex Wind Farms

Zhongguo dianli
According to the evaluation of onshore wind energy resources, the hub height of the wind turbine is greater than the height of the wind tower. The influences of atmospheric stability and surface roughness changes are ignored, and the wind shear index is ...
Rui HU, Shuzhou WU, Yonghua LI, Jiafei QIAO   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source