Results 61 to 70 of about 2,979,616 (246)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Research of flux footprint of city based on the FSAM model

上海师范大学学报. 自然科学版, 2012
The research of urban ecological system carbon plays a very important role in global climate change area.In this study,based on the eddy covariance system of Shanghai′s peri-urban forest and FSAM model (the Flux-Source Area Model),the distribution of ...
YUAN Zhuangpeng, ZHAO Min
doaj  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Simulation Uncertainty of Near-Surface Wind Caused by Boundary Layer Parameterization Over the Complex Terrain

Frontiers in Energy Research, 2020
Accurate prediction of near-surface wind based on numerical weather prediction models is essential to promote efficient wind energy harvesting. In this study, the performances of different Boundary Layer (BL) schemes in Weather Research and Forecasting ...
Luyuan Chen, Guangwei Li, Feimin Zhang, Chenghai Wang   +3 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Continuous measurements of atmospheric oxygen and carbon dioxide on a North Sea gas platform [PDF]

, 2010
A new atmospheric measurement station has been established on the North Sea oil and gas production platform F3, 200 km north off the Dutch coast (54°51' N, 4°44' E).
Neubert, R.E.M.,, S. van der Laan, Meijer, H. A. J., R. E. M. Neubert, Laan-Luijkx, I.T., van der, Laan, S., van der, Laan-Luijkx, I.T. van der, Laan, S. van der, van der Laan, S., I. T. van der Laan-Luijkx, H. A. J. Meijer, van der Laan-Luijkx, I.T., Laan-Luijkx, I.T. van der,, Meijer, H.A.J., Laan, S. van der,, Meijer, H.A.J.,, van der Laan-Luijkx, I. T., Meijer, H.A.J.; id_orcid, Neubert, R.E.M., Neubert, R. E. M.   +19 more
core   +3 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Meteorological Data Mining and Synthesis for Supplementing On-Site Data for Regulatory Compliance

Energies
Many regulatory requirements add significant delay in the licensing of new nuclear power stations. One area of particular interest is the environmental impact of potential atmospheric release.
Ben Sonpon, Shoaib Usman, Joseph Smith, Sarah Kovaleski, Jason Wibbenmeyer   +4 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source