Results 31 to 40 of about 332 (147)
Synthesis of well-defined polypeptide-based diblock copolymers [PDF]
PolímerosWe report an efficient protocol to synthesize rod-coil diblock copolymers of an α-helical polypeptide and poly(4-vinyl pyridine) via a combination of “living” ring-opening polymerization of α-amino acid N-carboxyanhydrides at 0 °C, polymer end-group ...
Thuy Thu Truong +4 more
doaj +1 more source
Mechanochemical Activation of a Bridged‐Exciplex Optical Force Probe
Advanced Science, EarlyView.A bridged‐exciplex optical force probe is synthesized, switching from solvatochromic charge‐transfer emission in the latent state to intense locally excited emission upon activation. This dual photophysical response with additional changes in quantum yield and fluorescence lifetime enables precise environmental sensing and distinct optical readouts ...
Ronja Schumann +8 more
wiley +1 more source
Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source
Controlled Atom Transfer Radical Depolymerization
Advanced Science, EarlyView.Controlled atom transfer radical depolymerization allows for precise, uniform shortening of polymer chains to yield monomers on demand. By tuning catalyst concentration and temperature, this strategy prioritizes deactivation to maintain molecular weight control throughout depolymerization.
Dimitra Mantzara +4 more
wiley +1 more source
BiosensorsAtom transfer radical polymerization (ATRP) is a leading reversible deactivation radical polymerization method. It has become an emerging technology to synthesize well-defined, tailor-made polymers, promoting the development of advanced materials (e.g ...
Ning Xia +4 more
doaj +1 more source
Recent developments in atom transfer radical polymerization initiators for development of polymer-protein bioconjugates [PDF]
Journal of BioScience and Biotechnology, 2013 One of the major challenges in modern synthetic polymer chemistry is to synthesize end defined polymers of different end functionality with predetermined uniform molecular weight.
AKHILESH KUMAR SHAKYA, Ashok Kumar
doaj
BMC Chemistry, 2019 A newly modified paper-based enzyme-linked immunosorbent assay (P-ELISA) was established by immobilizing more proteins on the paper surface through an atom transfer radical polymerization (ATRP) reaction.
Lu Qi +4 more
doaj +1 more source
Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Angewandte Chemie International Edition, EarlyView.Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation
Angewandte Chemie International Edition, EarlyView.The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf +4 more
wiley +1 more source
Science and Technology of Advanced Materials, 2015 The grafting of poly(hydroxyethylmethacrylate) on polymeric porous membranes via atom transfer radical polymerization (ATRP) and subsequent modification with a photo-responsive spiropyran derivative is described.
Anja C Pauly +9 more
doaj +1 more source