Results 41 to 50 of about 187,307 (265)
Serum and Urine Copper – Contamination and Stability
Acta Medica Bulgarica, 2015 Pre-analytical factors of variation need to be carefully considered and investigated in efforts to harmonize all aspects of the total testing process. This study aimed to evaluate contamination and stability in copper (Cu) analysis of serum and urine by ...
Dimitrova Ivanova I. +7 more
doaj +1 more source
Química Nova, 2002 The historical development of atomic spectrometry techniques based on chemical vapor generation by both batch and flow injection sampling formats is presented.
Iracema Takase +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MethodsXCadmium is a common environmental heavy metal that is very toxic and carcinogenic for human and other flora and fauna. Therefore, this study is aimed to evaluate the fisibility of vermicompost fertilizer for cadmium uptake from soil by the root of radish
Ahmad Zarei, Hassan Reza Rokni
doaj +1 more source
Determination of lead concentration in chicken liver and breast tissues in a number of poultry farms in Qom and Semnan provinces [PDF]
Bihdāsht-i Mavādd-i Ghaz̠āyī, 2019 Poultry meat is considered as a source of animal protein with high biological amino acids, many vitamins, and minerals. Food contamination with heavy metals is a major threat to humans and animals. Long-term exposure could have detrimental effects.
S. Faryabi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Determination of calcium in cements, by atomic absorption
Materiales de Construccion, 1975 Not ...
Fernando Triviño
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source