Results 31 to 40 of about 5,680,060 (316)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
MATEC Web of Conferences, 2016 The first developed method allowed to determine the combined effects of emissions of pollutants into the atmospheric air in the city by combined heat and power stations group, as well as to assess the interference impact of combined heat and power ...
Telichenko Valeriy +2 more
doaj +1 more source
Nuclear Engineering and Technology, 2019 Probabilistic safety assessments (PSA) have been used for several decades to visualize the risk level of commercial nuclear power plants (NPPs). Since the role of a human reliability analysis (HRA) is to provide human error probabilities for safety ...
Jinkyun Park +6 more
doaj +1 more source
Non-hardening embrittlement mechanism of pressure vessel steel Ni-Cr-Mo-V welds during thermal aging
Advances in Mechanical Engineering, 2020 The mechanical performance of reactor pressure vessel materials is an important factor in the safety and economics of the operation of a nuclear power plant.
Guojun Wei +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Atomic Power Development Associates Report APDA-108 [PDF]
, 1955 Report that generally describes sodium cooled fast reactors, the features and facilities of such a reactor proposed by Atomic Power Development Associates, and then its safety and siting ...
Atomic Power Development Associates
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Scientific Reports, 2022 Particles containing alpha (α) nuclides were identified from sediment in stagnant water in the torus room of the Fukushima Dai-ichi Nuclear Power Station(FDiNPS)’s Unit 2 reactor.
Takumi Yomogida +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source