Results 51 to 60 of about 144,255 (267)

Developing an Integrated Model of Resilience and System Dynamics for NPP Accident [PDF]

open access: yesJournal of Systems Thinking in Practice
The Fukushima Daiichi nuclear power plant (FDNPP) accident highlights the role of resilience and system dynamics in maintaining the safety of nuclear power plants (NPP).
Muhammed Mufazzal Hossen
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Investigations on strength of piping for non-condensable gas combustion (Part 2: FEM analysis of steel pipes with a valve or an elbow subjected to hydrogen-oxygen detonation)

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Carbon steel pipe specimens, which had been experimentally ruptured or deformed by hydrogen-oxygen detonation, were analysed by dynamic analysis using a finite element method (FEM).
Akira NEBU   +5 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Analysis of Steam Line Break Accident Using PCTRAN Model of VVER-1200 NPP

open access: yesApplications of Modelling and Simulation, 2023
The investigation of thermal-hydraulic parameters during steam-line break (SLB) accidents is performed by applying the personal computer transient analyzer (PCTRAN) simulator model of the VVER-1200 nuclear power plant (NPP). Five cases, namely, 0.005 m2 (
Muhammed Mufazzal Hossen   +2 more
doaj  

Investigations on strength of piping for non-condensable gas combustion (Part 3: Estimation of fracture strain of steel pipes subjected to hydrogen-oxygen detonation)

open access: yesNihon Kikai Gakkai ronbunshu, 2015
To assess the integrity of piping under the detonation pressure of accumulated hydrogen-oxygen, the fracture strain of the pipe material must be identified.
Akira NEBU   +5 more
doaj   +1 more source

Public Power and Atomic Power Development

open access: yesLaw and Contemporary Problems, 1956
A jumble of questions of law, politics, public opinion, economics, and ideology make the subject of public power a rich and confused field of debate. This paper is not concerned with the merits of that debate; it is concerned rather with a lawyer's appraisal of the Atomic Energy Act of I954 as that law relates to public-power issues.
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Recent verification activities on probabilistic fracture mechanics analysis code PASCAL4 for reactor pressure vessel

open access: yesMechanical Engineering Journal, 2020
Probabilistic fracture mechanics (PFM) is considered a promising methodology in assessing the integrity of structural components in nuclear power plants because it can rationally represent the influence parameters in their probabilistic distributions ...
Kai LU   +8 more
doaj   +1 more source

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