Results 41 to 50 of about 5,453,079 (314)
Atomic Power Development Associates Report APDA-108 [PDF]
, 1955 Report that generally describes sodium cooled fast reactors, the features and facilities of such a reactor proposed by Atomic Power Development Associates, and then its safety and siting ...
Atomic Power Development Associates
core
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Nuclear Engineering and Technology, 2019 Probabilistic safety assessments (PSA) have been used for several decades to visualize the risk level of commercial nuclear power plants (NPPs). Since the role of a human reliability analysis (HRA) is to provide human error probabilities for safety ...
Jinkyun Park +6 more
doaj +1 more source
Non-hardening embrittlement mechanism of pressure vessel steel Ni-Cr-Mo-V welds during thermal aging
Advances in Mechanical Engineering, 2020 The mechanical performance of reactor pressure vessel materials is an important factor in the safety and economics of the operation of a nuclear power plant.
Guojun Wei +4 more
doaj +1 more source
Atomic Power Development Associates Report APDA-124 [PDF]
, 1960 Report describing the Enrico Fermi Atomic Power Plant, its fast breeder reactor, and heat transport ...
Atomic Power Development Associates
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
MATEC Web of Conferences, 2016 The first developed method allowed to determine the combined effects of emissions of pollutants into the atmospheric air in the city by combined heat and power stations group, as well as to assess the interference impact of combined heat and power ...
Telichenko Valeriy +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source