Results 61 to 70 of about 5,453,079 (314)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Public Power and Atomic Power Development

Law and Contemporary Problems, 1956
A jumble of questions of law, politics, public opinion, economics, and ideology make the subject of public power a rich and confused field of debate. This paper is not concerned with the merits of that debate; it is concerned rather with a lawyer's appraisal of the Atomic Energy Act of I954 as that law relates to public-power issues.
openaire   +2 more sources

Atomic Energy Commission Report AECD-3792

, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from March to May ...
Knolls Atomic Power Laboratory
core  

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Ti₃C₂T_x-Based Materials and Coatings for De-Icing and Defogging of Wind Turbine Blades: Materials Basis, Structural Design, Engineering Integration, and Future Opportunities

Nanomaterials
In cold, humid environments, even a small amount of ice accumulation on the blade surface can degrade aerodynamic performance, increase drag, induce premature stall and vibration, and raise the risks of shutdown, fatigue, and ice throw.
Weiwei Wu, Kening Peng, Kunqi Zhang, Zhifang Liu, Nana Yao   +4 more
doaj   +1 more source

Recent verification activities on probabilistic fracture mechanics analysis code PASCAL4 for reactor pressure vessel

Mechanical Engineering Journal, 2020
Probabilistic fracture mechanics (PFM) is considered a promising methodology in assessing the integrity of structural components in nuclear power plants because it can rationally represent the influence parameters in their probabilistic distributions ...
Kai LU, Jinya KATSUYAMA, Yinsheng LI, Yuhei MIYAMOTO, Takatoshi HIROTA, Yu ITABASHI, Masaki NAGAI, Masahide SUZUKI, Yasuhiro KANTO   +8 more
doaj   +1 more source

Nuclear Physics Section Progress Report

, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from September to November ...
Knolls Atomic Power Laboratory
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Development of multigroup cross section library generation system TPAMS

Nuclear Engineering and Technology
Kylin-2 is an advanced neutronics lattice code, developed by Nuclear Power Institute of China. High-precision multigroup cross section library is need for KYLIN-2 to carry out simulation of current pressurized water reactor (PWR) and advanced reactor. In
Lili Wen, Haicheng Wu, Ying Chen, Xiaoming Chai, Xiaofei Wu, Xiaolan Tu, Yuan Liu   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source