Results 81 to 90 of about 812,972 (298)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Investigation of conventional and Super-X divertor configurations of MAST Upgrade using SOLPS
, 2014 One of the first studies of MAST Upgrade divertor configurations with SOLPS5.0 are presented. We focus on understanding main prospects associated with the novel geometry of the Super-X divertor (SXD).
Fishpool, G +4 more
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Applied SciencesThis study addresses the operational degradation of reinforced concrete structures of buildings and facilities where radioactive materials and waste are handled, if degradation is caused by the joint effect of ionizing radiation from materials ...
Rustem Omarov +2 more
doaj +1 more source
The effect of leveling coatings on the atomic oxygen durability of solar concentrator surfaces [PDF]
Space power systems for Space Station Freedom will be exposed to the harsh environment of low earth orbit (LEO). Neutral atomic oxygen is the major constituent in LEO and has the potential of severely reducing the efficiency of solar dynamic power ...
Degroh, Kim K. +2 more
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
AerospaceWith the in-depth study of the unique flight ability of bats in the field of bionic robots, wind-tunnel experiments have become an important means to verify the feasibility of bat-like flying robot structures.
Bosong Duan +4 more
doaj +1 more source
Laser Cooling by Collisional Redistribution of Radiation
, 2009 The general idea that optical radiation may cool matter was put forward by Pringsheim already in 1929. Doppler cooling of dilute atomic gases is an extremely successful application of this concept, and more recently anti-Stokes cooling in multilevel ...
Vogl, Ulrich, Weitz, Martin
core +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
From Cosmology to Cold Atoms: Observation of Sakharov Oscillations in Quenched Atomic Superfluids
, 2012 Sakharov oscillations, conventionally discussed in the context of early universe evolution and the anisotropy of cosmic microwave background radiation, is the manifestation of interfering acoustic waves synchronously generated in an ideal fluid.
C. Chin +9 more
core +1 more source