Results 81 to 90 of about 818,442 (297)

Recent verification activities on probabilistic fracture mechanics analysis code PASCAL4 for reactor pressure vessel

open access: yesMechanical Engineering Journal, 2020
Probabilistic fracture mechanics (PFM) is considered a promising methodology in assessing the integrity of structural components in nuclear power plants because it can rationally represent the influence parameters in their probabilistic distributions ...
Kai LU   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Coordination motifs and large-scale structural organization in atomic clusters

open access: yes, 2008
The structure of nanoclusters is complex to describe due to their noncrystallinity, even though bonding and packing constraints limit the local atomic arrangements to only a few types.
D. J. Wales   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Development of multigroup cross section library generation system TPAMS

open access: yesNuclear Engineering and Technology
Kylin-2 is an advanced neutronics lattice code, developed by Nuclear Power Institute of China. High-precision multigroup cross section library is need for KYLIN-2 to carry out simulation of current pressurized water reactor (PWR) and advanced reactor. In
Lili Wen   +6 more
doaj   +1 more source

Theory for atomic diffusion on fixed and deformable crystal lattices

open access: yes, 1999
We develop a theoretical framework for the diffusion of a single unconstrained species of atoms on a crystal lattice that provides a generalization of the classical theories of atomic diffusion and diffusion-induced phase separation to account for ...
Fried, Eliot, Sellers, Shaun
core   +1 more source

Calculations of Energy Losses due to Atomic Processes in Tokamaks with Applications to the ITER Divertor

open access: yes, 1995
Reduction of the peak heat loads on the plasma facing components is essential for the success of the next generation of high fusion power tokamaks such as the International Thermonuclear Experimental Reactor (ITER) 1 .
D. Post   +5 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Generation and detection of a sub-Poissonian atom number distribution in a one-dimensional optical lattice

open access: yes, 2014
We demonstrate preparation and detection of an atom number distribution in a one-dimensional atomic lattice with the variance $-14$ dB below the Poissonian noise level.
Appel, J.   +6 more
core   +1 more source

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