Results 71 to 80 of about 812,972 (298)

Recent verification activities on probabilistic fracture mechanics analysis code PASCAL4 for reactor pressure vessel

Mechanical Engineering Journal, 2020
Probabilistic fracture mechanics (PFM) is considered a promising methodology in assessing the integrity of structural components in nuclear power plants because it can rationally represent the influence parameters in their probabilistic distributions ...
Kai LU, Jinya KATSUYAMA, Yinsheng LI, Yuhei MIYAMOTO, Takatoshi HIROTA, Yu ITABASHI, Masaki NAGAI, Masahide SUZUKI, Yasuhiro KANTO   +8 more
doaj   +1 more source

Calculations of Energy Losses due to Atomic Processes in Tokamaks with Applications to the ITER Divertor

, 1995
Reduction of the peak heat loads on the plasma facing components is essential for the success of the next generation of high fusion power tokamaks such as the International Thermonuclear Experimental Reactor (ITER) 1 .
D. Post, Hulse R., J. Abdallah, Jensen R. V., N. Putvinskaya, R. E. H. Clark   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Generation and detection of a sub-Poissonian atom number distribution in a one-dimensional optical lattice

, 2014
We demonstrate preparation and detection of an atom number distribution in a one-dimensional atomic lattice with the variance $-14$ dB below the Poissonian noise level.
Appel, J., Bookjans, E., Béguin, J. -B., Christensen, S. L., Müller, J. H., Polzik, E. S., Sørensen, H. L.   +6 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Development of multigroup cross section library generation system TPAMS

Nuclear Engineering and Technology
Kylin-2 is an advanced neutronics lattice code, developed by Nuclear Power Institute of China. High-precision multigroup cross section library is need for KYLIN-2 to carry out simulation of current pressurized water reactor (PWR) and advanced reactor. In
Lili Wen, Haicheng Wu, Ying Chen, Xiaoming Chai, Xiaofei Wu, Xiaolan Tu, Yuan Liu   +6 more
doaj   +1 more source

Theory for atomic diffusion on fixed and deformable crystal lattices

, 1999
We develop a theoretical framework for the diffusion of a single unconstrained species of atoms on a crystal lattice that provides a generalization of the classical theories of atomic diffusion and diffusion-induced phase separation to account for ...
Fried, Eliot, Sellers, Shaun
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Molecular-orbital theory for the stopping power of atoms in the low velocity regime:the case of helium in alkali metals

, 1993
A free-parameter linear-combination-of-atomic-orbitals approach is presented for analyzing the stopping power of slow ions moving in a metal. The method is applied to the case of He moving in alkali metals.
A. Arnau, A.D. Sutton, D.A. Papaconstantopoulos, D.E. Meltzer, E. Clementi, E. Fermi, E. Rutheford, E. Rutheford, E.C. Goldberg, E.J. Williams, F. Flores, F. Flores, F. Sols, F.J. García Vidal, G. Peter Lepage, H. Wormeester, H.A. Bethe, J. Lindhard, J.A. Majewshi, J.R. Sabin, José J. Dorado, P. Bauer, P.L. Grande, P.M. Echenique, P.M. Echenique, P.O. Löwdin, R.H. Ritchie, S.F. Boys, W. A. Harrison, W. Brant   +29 more
core   +1 more source