Results 81 to 90 of about 6,969,361 (336)
Mechanical Engineering Journal, 2020 Probabilistic fracture mechanics (PFM) is considered a promising methodology in assessing the integrity of structural components in nuclear power plants because it can rationally represent the influence parameters in their probabilistic distributions ...
Kai LU +8 more
doaj +1 more source
A Miniature Cold-Atom Frequency Standard [PDF]
arXiv, 2011 Atomic sensors employing cold-atom technology enable unprecedented accuracy and resolution for next generation atomic clocks, magnetometers, gravimeters, and gyroscopes. To date, however, the size and complexity of cold atom systems have prevented their deployment in practical applications outside of large research laboratories.
arxiv
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
Atoms and associated spectral properties for positive operators on L^p [PDF]
arXiv, 2023 Inspired by Schwartz, Jang-Lewis and Victory, who study in particular generalizations of triangularizations of matrices to operators, we shall give for positive operators on Lebesgue spaces equivalent definitions of atoms (maximal irreducible sets). We also characterize positive power compact operators having a unique non-zero atom which appears as a ...
arxiv
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma +3 more
wiley +1 more source
Russian Journal of Economics and Law, 2007 The article is dedicated to the analysis of certain signs of the objective part of corpus delicti of the safety regulations violations at the atomic power objects: the deed, its consequences, casual relations between them, crime scene.
R. R. Fazylov
doaj
High-power doughnut beam generation for atom-funnel experiment [PDF]
arXiv, 2003 We have generated high power doughnut beam suitable for atom funnel experiment with the conversion efficiency of about 50 %.
arxiv