Results 31 to 40 of about 199,926 (265)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Stark broadening of N II spectral lines [PDF]
Serbian Astronomical JournalThe Stark broadening parameters, widths, and shifts, for spectral lines within the 45 N II multiplets, were calculated for collisions with electrons, protons and helium ions, by using the semiclassical perturbation method. The obtained data were
Dimitrijević Milan S. +2 more
doaj +1 more source
Astronomy, 2023 Natural systems of units {Ui} need to be overhauled to include the dimensionless coupling constants {αUi} of the natural forces. Otherwise, they cannot quantify all the forces of nature in a unified manner. Thus, each force must furnish a system of units
Dimitris M. Christodoulou +1 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Facile fabrication of self-assembled monolayers of organosilanes for antibiofilm applications
Results in Surfaces and InterfacesBiofilm is a conglomeration of microbial cells, encased in extracellular polymeric matrix. Biofilm formation at solid-liquid interfaces is imminent to microfouling and poses serious operational problems in various industrial, clinical and environmental ...
Alwar Ramanujam Padmavathi +5 more
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Stark Broadening of N VI Spectral Lines
Universe, 2023 Stark broadening parameters, line widths and shifts, for 15 N VI multiplets are calculated using semiclassical perturbation theory for temperatures from 50,000 K to 2,000,000 K, and perturber density of 1016 cm−3. As perturbers have been taken electrons,
Milan S. Dimitrijević +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source