Results 41 to 50 of about 200,380 (264)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Extended Photoionization Cross Section Calculations for C III
Applied SciencesSpectral features of photoionization of various levels of C III are reported. These include characteristics of Rydberg and Seaton resonances, low and high excited levels, lifetimes, and total and partial cross sections.
V. Stancalie
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Recent Results for Widths of Lines Important in the Spectra of Cool Stars
Open Astronomy, 2011 The broadening of spectral lines by neutral perturbers is an important factor in the interpretation of the observed spectra of cool stars and is often included in the analysis by using a simple van der Waals formula. Detailed calculations are carried out
Peach G.
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Atoms, 2018 In this contribution, we present results of bound state transition modeling using the cut-off Coulomb model potential. The cut-off Coulomb potential has proven itself as a model potential for the dense hydrogen plasma.
Nenad M. Sakan +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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Charge transfer in C + O+ collisions and its impact on supernova spectra
Astronomy & AstrophysicsThe charge-transfer process C + O+ → C+ + O (1D) has been found in previous modelling to be important in neutralising oxygen ions in supernova (SN) ejecta, as well as in determining the strength of the [O I] doublet at 6300 and 6364 Å. This conclusion is,
Reja Deboki +3 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
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