Results 41 to 50 of about 560 (265)
Controvérsias sobre o atomismo no século XIX Controversies on atomism in the nineteenth century
Química Nova, 2009 The present article reviews aspects of the controversy in nineteenth-century physical sciences between atomists and anti-atomists, and the scientific, philosophical and methodological aspects about the atomic debates.
Maria da Conceição Marinho Oki
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Les Dossiers du GRIHL, 2010 Anna Rita Capoccia's contribution is based on the analysis of manuscripts created by Giulio Gori and other Jesuit professors at Roman College in the first twenty years of eighteenth century.There are here described professors' "hidden" opposition to ...
Anna Rita Capoccia
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Deleuze and Epicurean Philosophy: Atomic Speed and Swerve Speed
Journal of French and Francophone Philosophy, 2013 This paper reconstructs Gilles Deleuze’s interpretation of Epicurean atomism, and explicates his claim that it represents a problematic idea, similar to the idea exemplified in early, “barbaric” accounts of the differential calculus.
Michael James Bennett
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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KANT AND THE «SPIRIT OF EPICURUS» (IN KANT’S PRE-CRITICAL AND CRITICAL PHILOSOPHY)
Концепт: философия, религия, культура, 2018 In the first part of the article, the relation of the ethics of Epicurus to Kant's practical philosophy is considered. Analyzing the principles on which the notion of the supreme good of the ancients was built, Kant paid special attention to the ...
V. A. Ter-Arakeliantz, A. V. Yukhno
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Mechanistic Trends in Chemistry
Substantia, 2018 During the twentieth century, the mechanistic worldview came under attack mainly because of the rise of quantum mechanics but some of its basic characteristics survived and are still evident within current science in some form or other.
Louis Caruana SJ
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