Results 141 to 150 of about 321,909 (338)
Allergic rhinitis as a systemic disease of respiratory tract
Journal of Education, Health and Sport, 2019 Allergic rhinitis affects nearly 500 million people in the world and is now considered not only to be a local catarrh of the nasal passages, but a chronic systemic respiratory disease.
Eleni Jasiukiewicz +2 more
doaj +1 more source
Advanced Science, EarlyView.This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
wiley +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Clinics and PracticeBackground/Objectives: Recently, epigenetic mechanisms have been recognized as crucial in atopic dermatitis development. The emphasis of this research was on expanding existing knowledge about the epigenetic aspects of atopic dermatitis, as well as ...
Sanja Jakovljevic +4 more
doaj +1 more source
Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
Advanced Science, EarlyView.This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan +24 more
wiley +1 more source
TNOA Journal of Ophthalmic Science and ResearchObjective: To know the demography and clinical profile of patients of vernal keratoconjunctivitis (VKC) in a tertiary care center over a period of 6 months from April 2023 to September 2023.
Manpreet Kaur +2 more
doaj +1 more source
Advanced Science, EarlyView.The redox‐active nature of NiOx enables ultrafast oxidative doping of spiro‐OMeTAD within seconds. Concurrently, NiOx‐Li+ coordination complexes formed during this redox process are selectively removed by filtration, effectively extracting residual Li+ ions from the film.
Yun Seop Shin +19 more
wiley +1 more source
Advanced Science, EarlyView.Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao +7 more
wiley +1 more source
A Review of Dupilumab in the Treatment of Atopic Dermatitis in Infants and Children
Drug Design, Development and TherapyMingyue Wang,1– 4 Xing-Hua Gao,1– 4 Li Zhang1 1Department of Dermatology, the First Hospital of China Medical University, Shenyang, 110001, People’s Republic of China; 2NHC Key Laboratory of Immunodermatology, China Medical University, Shenyang, People’s
Wang M, Gao XH, Zhang L
doaj
Advanced Science, EarlyView.We show that interfacial oxygen at the MgO/Fe interface can be transformed from an uncontrolled variable into a tunable design parameter for spintronic junctions. Momentum microscopy provides direct access to the momentum‐ and spin‐resolved electronic structure beneath the insulating MgO layers, revealing how oxygen intercalation reshapes buried Fe ...
David Maximilian Janas +14 more
wiley +1 more source