Results 71 to 80 of about 133,914 (162)

Chronic cough, itch, skin pain and other unpleasant skin sensations are frequently associated: Results from survey on 8077 individuals

JEADV Clinical Practice
Background Neuronal sensitisation frequently occurs in patients with pain, itch and cough. Objectives To study the association of chronic pruritus, as well as other unpleasant skin sensations (especially skin pain), and chronic cough.
Anne‐Sophie Ficheux, Emilie Brenaut, Charles Taieb, Laurent Misery   +3 more
doaj   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3819-3830, November 2026.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, Volume 31, Issue 11, Page 1077-1090, November 2026.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families [PDF]

, 2008
Recent studies have identified 2 loss-of-function variants, R501X and 2282del4, in the filaggrin gene as predisposing factors in the development of eczema.
Link, Jenny, Lee, Simon P., Lieden, Agne, M D'Amato, Ekelund, Elisabeth, Kockum, Ingrid, SP Lee, D'Amato, Mauro, I Kockum, CNA Palmer, Bradley, Maria, A Liedén, E Ekelund, J Link, M Bradley, Palmer, Colin N. A.; id_orcid, Lieden, A, Link, J,, Kochum, I, Palmer, CNA, Lee, SP, Bradley, M, D'Amato, M, Ekelund, E   +23 more
core   +1 more source

Effectiveness of the P2X3 Antagonist Gefapixant for Refractory Atopic Cough: A Retrospective Cohort Study

Journal of Asthma and Allergy
Yoshihisa Ishiura,1,2 Shosaku Nomura,1,2 Noriyuki Ohkura,3 Johsuke Hara,3 Masaki Fujimura,3 Tomoki Ito1,2 1First Department of Internal Medicine, Kansai Medical University, Osaka, Japan; 2Respiratory Medicine, Kansai Medical University Medical Center ...
Ishiura Y, Nomura S, Ohkura N, Hara J, Fujimura M, Ito T   +5 more
doaj  

Efficacy of Gefapixant, a P2X₃ Antagonist, for Refractory Atopic Cough. [PDF]

Int Med Case Rep J, 2023
Ishiura Y, Nomura S, Ishii Y, Imai K, Sawai Y, Tamaki T, Shimizu T, Miyashita N, Ito T.   +8 more
europepmc   +1 more source

Functional Magnetic Nerve Stimulation: The development of a method of generation of explosive expiratory flows in the intubated patient through abdominal muscle stimulation. [PDF]

, 2012
Functional Magnetic Nerve Stimulation: The development of a method of generation of explosive expiratory flows in the intubated patient through abdominal muscle stimulation.
Turnbull, David
core   +3 more sources

Screening survey of ocular, nasal, respiratory and skin symptoms in manicurists in Poland

International Journal of Occupational Medicine and Environmental Health, 2017
Objectives: Manicurists are exposed to various chemicals in nail and skin care products and may develop ocular, nasal, respiratory or skin adverse reactions to them.
Marta Kieć-Świerczyńska, Dominika Świerczyńska-Machura, Dorota Chomiczewska-Skóra, Beata Kręcisz, Jolanta Walusiak-Skorupa   +4 more
doaj   +1 more source

Use Klein's Cough Drops

, 2023
Trade card/ink blotter advertising Klein's Cough Drops, a remedy prepared by Klein's Cough Drop Company, St ...

core  

Role of a Th2 cytokine inhibitor in asthma treatment

Allergology International, 2004
The airway wall of asthmatic patients is infiltrated with inflammatory cells, consisting chiefly of eosinophils and T lymphocytes. Among these T lymphocytes, Th2 cells are involved in the regulation of the IgE immune response and local allergic ...
Jun Tamaoki
doaj   +1 more source