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Nature Reviews Disease Primers, 2018 Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious ...
Stephan Weidinger +2 more
exaly +9 more sources
Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
Nature Reviews Drug Discovery, 2021 Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains challenging to treat owing to the limited response to available therapies.
Thomas Bieber
exaly +2 more sources
Cutis, 2021 A) Pink scaling plaques and erythematous erosions in the antecubital fossae of a 6-year-old White boy. B) Violaceous, hyperpigmented, nummular plaques on the back and extensor surface of the right arm of a 16-month-old Black girl. C) Atopic dermatitis and follicular prominence/accentuation on the neck of a young Black girl.
S. Ständer
semanticscholar +7 more sources
Acta bio-medica : Atenei Parmensis, 2020 Atopic dermatitis (AD) is a common inflammatory skin disease, clinically characterized by recurrent eczematous lesions and intense itching, leading to excoriations and susceptibility to cutaneous infections. Although it is considered a pediatric disorder, mainly starting in infancy, it is also very common in adults.
S. Langan, A. Irvine, S. Weidinger
semanticscholar +6 more sources
Magnitude of atopic dermatitis and associated factors among children in northwest Ethiopia [PDF]
Scientific ReportsAtopic dermatitis is a chronic inflammatory skin disease that typically begins in infancy and extends into adulthood in a small proportion of cases. Around 20% of children and 5% of adults worldwide suffer from atopic dermatitis.
Alemu Bezabih Tegegnie +4 more
doaj +2 more sources
Allergy, Asthma & Clinical Immunology, 2011 Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious ...
Wade Watson, Sandeep Kapur
openaire +6 more sources
New England Journal of Medicine, 2008 Atopic dermatitis (AD) is a chronic and relapsing disease affecting an increasing number of patients. Usually starting in early childhood, AD can be the initial step of the so-called atopic march, i.e. followed by allergic rhinitis and allergic asthma.
BUGGIANI, GIONATA +2 more
openaire +6 more sources
Acta Dermato-Venereologica, 2023 Clinical trials showed that upadacitinib, a selective Janus kinase-1 inhibitor, is effective for treatment of moderate-to-severe atopic dermatitis. However, daily practice studies are limited.
Celeste M. Boesjes +8 more
doaj +1 more source
Molecular Mechanisms of Atopic Dermatitis Pathogenesis
International Journal of Molecular Sciences, 2021 Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic feature is persistent itching of the skin. The chronic, relapsing course of the disease, economic burden, and the whole family’s involvement in the treatment process ...
Jowita Sroka-Tomaszewska, M. Trzeciak
semanticscholar +1 more source