Increasing prevalence of asthma diagnosis and symptoms in children is confined to mild symptoms [PDF]
BACKGROUND: The prevalence of childhood asthma is increasing but few studies have investigated trends in asthma severity. We investigated trends in asthma diagnosis and symptom morbidity between an eight year time period in a paired prevalence study.
Billings, C. +7 more
core +2 more sources
Recent advances of non‐invasive sensors for smart wearable respiratory monitoring
Respiration contains rich physiological and pathological information, making it one of the most fundamental and continuous vital signs. Respiration monitoring is a non‐invasive and simple, but incredibly powerful, tool for assessing health, managing disease, and tracking fitness.
Jianhui Chen +8 more
wiley +1 more source
Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology +4 more
wiley +1 more source
Environmental Exposure to Endotoxin and Decreased Risk of Childhood Atopy
The hygiene hypothesis implies, in immunological terms, that microbial stimulation in early life skews the immune system towards the development of a T helper type 1 (Th1)-type lymphocyte population, and away from a T helper type 2 (Th2)-type development
Tatsuo Sakamoto +5 more
doaj +1 more source
Immune factors preceding diagnosis of glioma: a Prostate Lung Colorectal Ovarian Cancer Screening Trial nested case-control study. [PDF]
BackgroundEpidemiological studies of adult glioma have identified genetic and environmental risk factors, but much remains unclear. The aim of the current study was to evaluate anthropometric, disease-related, and prediagnostic immune-related factors for
Bracci, Paige M +8 more
core
Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang +9 more
wiley +1 more source
TSLP Expression: Cellular Sources, Triggers, and Regulatory Mechanisms
Thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine initially identified in the culture supernatant of a thymic stromal cell line. Highly expressed in the epidermis in skin lesions of atopic dermatitis patients, TSLP was subsequently found to be
Toshiro Takai
doaj +1 more source
Natural History of Airway Hyperresponsiveness and Its Association With Asthma Traits. [PDF]
AHR improves in most children over adolescence when its relationship with asthma changes. AHR is better at ruling out asthma in children, while it is superior at ruling in asthma in young adults. Age should be considered when interpreting AHR, and different cutoffs might be required for children and adults.
Carra S +3 more
europepmc +2 more sources
OBJECTIVE: To assess the validity of a food frequency questionnaire (FFQ) by applying it to children and adolescents living in Salvador, Bahia. METHODS: The validity of this FFQ with 98 food items was investigated among 108 children and adolescents who ...
Assis, AMO +8 more
core +2 more sources
Vitamin A supplementation and risk of atopy:long-term follow-up of a randomized trial of vitamin A supplementation at six and nine months of age [PDF]
BACKGROUND: The World Health Organization recommends high-dose vitamin A supplementation (VAS) for children above six months of age in low-income countries. VAS has been associated with up-regulation of the Th2 response.
Aaby, Peter +5 more
core +1 more source

