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Indole Peptidomimetics Show Potent and Selective Activity against Drug-Resistant <i>Plasmodium falciparum</i>. [PDF]
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Drug repurposing of Mito-Atovaquone for cancer treatment.
Pharmaceutical Patent Analyst, 2023Repurposing of approved drugs in a new strategy to combat cancer that leads to savings in time and investment. Atovaquone is a US FDA approved drug for treatment of Pneumocystis carinii pneumonia and malaria.
N. Villa‐Ruano +4 more
semanticscholar +1 more source
Antiviral Research, 2023
The antimalarial drug atovaquone was recently reported to inhibit the in vitro replication of different arboviruses, including chikungunya virus (CHIKV) and Zika virus (ZIKV). Furthermore, atovaquone was shown to block Plasmodium parasite transmission by
Lanjiao Wang +5 more
semanticscholar +1 more source
The antimalarial drug atovaquone was recently reported to inhibit the in vitro replication of different arboviruses, including chikungunya virus (CHIKV) and Zika virus (ZIKV). Furthermore, atovaquone was shown to block Plasmodium parasite transmission by
Lanjiao Wang +5 more
semanticscholar +1 more source
Annals of Pharmacotherapy, 1993
OBJECTIVE: To review the chemistry, pharmacology, pharmacokinetics, clinical efficacy, and safety of atovaquone. DATA IDENTIFICATION: An English-language literature search using MEDLINE (1984-1993), programs and abstracts of the 30th ...
L G, Haile, J F, Flaherty
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OBJECTIVE: To review the chemistry, pharmacology, pharmacokinetics, clinical efficacy, and safety of atovaquone. DATA IDENTIFICATION: An English-language literature search using MEDLINE (1984-1993), programs and abstracts of the 30th ...
L G, Haile, J F, Flaherty
openaire +2 more sources
International journal of clinical pharmacology and therapeutics, 2023
OBJECTIVE At our institution, patients with hematological disease who require Pneumocystis jirovecii pneumonia (PJP) prophylaxis were administered atovaquone at a low dose (750 mg/day).
Tomiyuki Sugi +6 more
semanticscholar +1 more source
OBJECTIVE At our institution, patients with hematological disease who require Pneumocystis jirovecii pneumonia (PJP) prophylaxis were administered atovaquone at a low dose (750 mg/day).
Tomiyuki Sugi +6 more
semanticscholar +1 more source
Pathology, Research and Practice, 2021
The poor outcomes in ovarian cancer necessitate new treatments. Strategies to interfere with oxidative phosphorylation have been recently highlighted for the treatment of ovarian tumors.
Yue Guo, Bo Hu, Bingbing Fu, Hongyan Zhu
semanticscholar +1 more source
The poor outcomes in ovarian cancer necessitate new treatments. Strategies to interfere with oxidative phosphorylation have been recently highlighted for the treatment of ovarian tumors.
Yue Guo, Bo Hu, Bingbing Fu, Hongyan Zhu
semanticscholar +1 more source
Journal of Infectious Diseases
Human babesiosis is a potentially fatal tick-borne disease caused by intraerythrocytic Babesia parasites. The emergence of resistance to recommended therapies highlights the need for new and more effective treatments.
P. Vydyam +6 more
semanticscholar +1 more source
Human babesiosis is a potentially fatal tick-borne disease caused by intraerythrocytic Babesia parasites. The emergence of resistance to recommended therapies highlights the need for new and more effective treatments.
P. Vydyam +6 more
semanticscholar +1 more source