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The Trypanocidal Activity of Naphthoquinones: A Review [PDF]

open access: yesMolecules, 2009
Naphthoquinones are compounds present in several families of higher plants. Their molecular structures confer redox properties, and they are involved in multiple biological oxidative processes.
Solange L De Castro
exaly   +5 more sources

The Relevance and Insights on 1,4-Naphthoquinones as Antimicrobial and Antitumoral Molecules: A Systematic Review

open access: yesPharmaceuticals, 2023
Natural product derivatives are essential in searching for compounds with important chemical, biological, and medical applications. Naphthoquinones are secondary metabolites found in plants and are used in traditional medicine to treat diverse human ...
Gabriela Navarro-Tovar   +2 more
exaly   +3 more sources

In Vitro Evaluation of Natural Sesquiterpene Lactones and Naphthoquinones Against Pancreatic Ductal Adenocarcinoma Cells [PDF]

open access: yesMolecules
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, highlighting the need to identify novel bioactive compounds with antitumor potential. Natural products constitute a valuable source of molecules with anticancer activity.
Nadia T. Mirakian   +12 more
doaj   +2 more sources

Naphthoquinones as a Promising Class of Compounds for Facing the Challenge of Parkinson’s Disease

open access: yesPharmaceuticals, 2023
Parkinson’s disease (PD) is a degenerative disease that affects approximately 6.1 million people and is primarily caused by the loss of dopaminergic neurons.
Thaís Barreto Santos   +6 more
doaj   +1 more source

Synthesis of 4-Aryl-1,2-naphthoquinones via a conjugate addition-oxidation reaction catalyzed by p-toluenesulfonic acid

open access: yesResults in Chemistry, 2022
A catalytic conjugate addition-oxidation reaction of 1,2-naphthoquinones has been investigated. p-Toluenesulfnoic acid was found to be the most effective catalyst for the reaction.
Watcharapon Prasitwatcharakorn   +2 more
doaj   +1 more source

1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis

open access: yesBeilstein Journal of Organic Chemistry, 2022
Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being ...
Ruan Carlos B. Ribeiro   +5 more
doaj   +1 more source

Determination of the Active Chemical Compounds and the Antibacterial Activity of Various Fractions of Lawsonia inermis L.

open access: yesBorneo Journal of Pharmacy, 2022
Lawsonia inermis L., or henna leaves, are usually used to treat wounds on the skin. Lawsonia inermis contain naphthoquinones, flavonoids, tannins, and saponins.
Sri Mulyaningsih   +1 more
doaj   +1 more source

1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling

open access: yesMolecules, 2014
Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling. Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione ...
Lars-Oliver Klotz   +2 more
doaj   +1 more source

Cytotoxicity, hemolysis and in vivo acute toxicity of 2-hydroxy-3-anilino-1,4-naphthoquinone derivatives

open access: yesToxicology Reports, 2016
The 1,4-naphthoquinones, important members of the family of quinones are used as both crude extracts and as compound manipulated by the pharmaceutical industry.
Valeska Santana de Sena Pereira   +5 more
doaj   +1 more source

Modulation of basophils' degranulation and allergy-related enzymes by monomeric and dimeric naphthoquinones.

open access: yesPLoS ONE, 2014
Allergic disorders are characterized by an abnormal immune response towards non-infectious substances, being associated with life quality reduction and potential life-threatening reactions.
Brígida R Pinho   +4 more
doaj   +1 more source

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