Results 1 to 10 of about 4,751 (182)
The Trypanocidal Activity of Naphthoquinones: A Review [PDF]
Molecules, 2009 Naphthoquinones are compounds present in several families of higher plants. Their molecular structures confer redox properties, and they are involved in multiple biological oxidative processes.
Solange Lisboa De Castro +1 more
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Pharmaceuticals, 2023 Natural product derivatives are essential in searching for compounds with important chemical, biological, and medical applications. Naphthoquinones are secondary metabolites found in plants and are used in traditional medicine to treat diverse human ...
Denisse De Loera +2 more
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Synthesis and Cytotoxic Evaluation of a Series of 2-Amino-Naphthoquinones against Human Cancer Cells
Molecules, 2014 The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 ...
Celso Amorim Camara +2 more
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In Vitro Evaluation of Natural Sesquiterpene Lactones and Naphthoquinones Against Pancreatic Ductal Adenocarcinoma Cells [PDF]
MoleculesPancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, highlighting the need to identify novel bioactive compounds with antitumor potential. Natural products constitute a valuable source of molecules with anticancer activity.
Nadia T. Mirakian +12 more
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Results in Chemistry, 2022 A catalytic conjugate addition-oxidation reaction of 1,2-naphthoquinones has been investigated. p-Toluenesulfnoic acid was found to be the most effective catalyst for the reaction.
Watcharapon Prasitwatcharakorn +2 more
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Naphthoquinones as a Promising Class of Compounds for Facing the Challenge of Parkinson’s Disease
Pharmaceuticals, 2023 Parkinson’s disease (PD) is a degenerative disease that affects approximately 6.1 million people and is primarily caused by the loss of dopaminergic neurons.
Thaís Barreto Santos +6 more
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1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis
Beilstein Journal of Organic Chemistry, 2022 Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being ...
Ruan Carlos B. Ribeiro +5 more
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Borneo Journal of Pharmacy, 2022 Lawsonia inermis L., or henna leaves, are usually used to treat wounds on the skin. Lawsonia inermis contain naphthoquinones, flavonoids, tannins, and saponins.
Sri Mulyaningsih +1 more
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1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling
Molecules, 2014 Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling. Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione ...
Lars-Oliver Klotz +2 more
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Toxicology Reports, 2016 The 1,4-naphthoquinones, important members of the family of quinones are used as both crude extracts and as compound manipulated by the pharmaceutical industry.
Valeska Santana de Sena Pereira +5 more
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