Identification of onosma visianii roots extract and purified shikonin derivatives as potential acaricidal agents against tetranychus urticae [PDF]
, 2017 There is an increasing need for the discovery of reliable and eco-friendly pesticides and natural plant-derived products may play a crucial role as source of new active compounds.
Benelli, S. +7 more
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Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites. [PDF]
, 2011 Our work on targeting redox equilibria of malarial parasites propagating in red blood cells has led to the selection of six 1,4-naphthoquinones, which are active at nanomolar concentrations against the human pathogen Plasmodium falciparum in culture and ...
Bauer, Holger +12 more
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Unveiling interactions between DNA and cytotoxic 2-arylpiperidinyl-1,4-naphthoquinone derivatives: A combined electrochemical and computational study [PDF]
, 2018 Indexación: Scopus.Three 2-arylpiperidinyl-1,4-naphthoquinone derivatives were synthesized and evaluated in vitro to determine their cytotoxicity on cancer and normal cell lines.
Canales, C. +4 more
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Toxicology Reports, 2016 The 1,4-naphthoquinones, important members of the family of quinones are used as both crude extracts and as compound manipulated by the pharmaceutical industry.
Valeska Santana de Sena Pereira +5 more
doaj +1 more source
Site of Prenylation Reaction in Synthesis of Phylloquinone (Vitamin K1) by Spinach Chloroplasts [PDF]
, 1981 In spinach chloroplasts, 1,4-dihydroxy-2-naphthoate is prenylated by phytyldiphosphate and subsequently methylated by S-adenosylmethionine to form phylloquinol.
Baldwin +22 more
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1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling
Molecules, 2014 Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling. Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione ...
Lars-Oliver Klotz +2 more
doaj +1 more source
Total synthesis of aurofusarin: studies on the atropisomeric stability of bis-naphthoquinones [PDF]
, 2018 An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin.
Allen +42 more
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PLoS ONE, 2014 Allergic disorders are characterized by an abnormal immune response towards non-infectious substances, being associated with life quality reduction and potential life-threatening reactions.
Brígida R Pinho +4 more
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Pharmaceuticals, 2022 Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host.
Lina S. Prieto Cárdenas +6 more
doaj +1 more source
Micropropagation for the production of high quality phytochemicals [PDF]
, 2013 Plants area source of many valuable secondary metabolites that find a broad field of applications, ranging from the agrochemical to the pharmaceutical industries.
Grevenstuk, Tomás, Romano, Anabela
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