Results 11 to 20 of about 6,879 (216)

Synthesis of branched naphthoquinones from castor oil

Orbital: The Electronic Journal of Chemistry, 2012
The naphthoquinones are cyclic aromatic α,β-dienonas with a basic framework derived from naphthalene. They are also found in many higher plants, algae, fungi and as the product of the  metabolism  of some  bacteria  having large biologica activity ...
Adriano Olímpio da Silva, Dênis P. de Lima, Rosangela da Silva Lopes, Ricardo Vieira de Lima, Roberto da Silva Gomes   +4 more
doaj   +2 more sources

The Antifungal Activity of Naphthoquinones: An Integrative Review

Anais da Academia Brasileira de Ciências
Naphthoquinones are the most commonly occurring type of quinones in nature. They are a diverse family of secondary metabolites that occur naturally in plants, lichens and various microorganisms.
DÉBORA O. FUTURO, PATRICIA G. FERREIRA, CAROLINE D. NICOLETTI, LUANA P. BORBA-SANTOS, FERNANDO C. DA SILVA, SONIA ROZENTAL, VITOR FRANCISCO FERREIRA   +6 more
doaj   +2 more sources

Activity of natural and synthetic naphthoquinones against Toxoplasma gondii, in vitro and in murine models of infection

Parasite, 2002
The effect of 14 natural and synthetic naphthoquinones in the replication of Toxoplasma gondii was evaluated. In vitro studies were accomplished in cultures of 2C4 fibroblasts infected with RH- strain.
Ferreira R.A., Oliveira A.B., Gualberto S.A., Vitor R.W.A.   +3 more
doaj   +2 more sources

Cytotoxicity of naphthoquinones and their capacity to generate reactive oxygen species is quenched when conjugated with gold nanoparticles

International Journal of Nanomedicine, 2011
Priya Srinivas1,2, Chitta Ranjan Patra2,4, Santanu Bhattacharya2, Debabrata Mukhopadhyay2,31Integrated Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala, India; 2Department of Biochemistry and Molecular Biology; 3Department of ...
Srinivas P, Patra CR, Bhattacharya S, Mukhopadhyay D   +3 more
doaj   +1 more source

Enantioselective Synthesis of Biaryl Atropisomers via the Addition of Thiophenols into Aryl-Naphthoquinones

, 2018
We report a cinchona alkaloid catalyzed addition of thiophenol into rapidly interconverting aryl-naphthoquinones, resulting in stable biaryl atropisomers upon reductive methylation.
Sean M. Maddox (1652338), Curtis E. Moore (1338609), Jeffrey L. Gustafson (1545544), Nicholas C. Rochester (5214203), Arnold L. Rheingold (1274736), Gregory A. Dawson (5214206), Arianna B. Ayonon (5214209)   +6 more
core   +4 more sources

Light-Driven Carbon–Carbon Coupling of α‑sp³–CH of Aliphatic Alcohols with sp²–CH Bond of 1,4-Naphthoquinones

, 2022
Here, an α-selective Csp3–H bond functionalization of primary aliphatic alcohols with 1,4-naphthoquinones yielded Csp2–Csp2 coupled products driven by blue-LED light under catalyst, metal, base, and reagent-free conditions.
Aditya Upadhyay (2621215), Saket Jain (9647983), Neena K A (13954295), Raushan Kumar Jha (13954289), Kanika (13954292), Sangit Kumar (1825567)   +5 more
core   +2 more sources

Ru(II)-Catalyzed [4 + 2]-Annulation and Arylation of 1,4-Naphthoquinones

, 2023
Naphthoquinones form the core of a variety of drugs and natural products. As a result, the conjugation of 1,4-naphthoquinones with organic building blocks would offer a facile strategy toward scaffolds of biological interest.
Akshay M. Nair, Shreemoyee Kumar, Shreemoyee Kumar (8543265), Akshay M. Nair (8543268), Chandra M. R. Volla, Chandra M. R. Volla (7354964), Jatin Patra (14627309), Jatin Patra   +7 more
core   +1 more source

Fe-Catalyzed Radical Trifluoromethyl-Alkenylation of Alkenes or Alkynes with 2‑Amino-1,4-naphthoquinones

, 2022
The first Fe-catalyzed three-component radical trifluoromethyl-alkenylation of alkenes with 2-amino-1,4-naphthoquinones and CF3SO2Na is reported.
Lingyun Zheng (4970980), Lin Tang (65412), Fang Yang (123514), Ge Lv (10998903), Shuai Zhang (115662), Qiuju Zhou (2251669)   +5 more
core   +1 more source

In Silico Antiprotozoal Evaluation of 1,4-Naphthoquinone Derivatives against Chagas and Leishmaniasis Diseases Using QSAR, Molecular Docking, and ADME Approaches

Pharmaceuticals, 2022
Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host.
Lina S. Prieto Cárdenas, Karen A. Arias Soler, Diana L. Nossa González, Wilson E. Rozo Núñez, Agobardo Cárdenas-Chaparro, Pablo R. Duchowicz, Jovanny A. Gómez Castaño   +6 more
doaj   +1 more source

Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors

Molecules, 2023
ATP acts in the extracellular environment as an important signal, activating a family of receptors called purinergic receptors. In recent years, interest in the potential therapeutics of purinergic components, including agonists and antagonists of ...
Paulo Anastácio Furtado Pacheco, Daniel Tadeu Gomes Gonzaga, Natalia Lidmar von Ranke, Carlos Rangel Rodrigues, David Rodrigues da Rocha, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Robson Xavier Faria   +7 more
doaj   +1 more source