Results 21 to 30 of about 4,751 (182)

Free Radical Scavenging Activity of Synthetic and Naturally Occurring Polyhydroxy-, Aminohydroxynaphthazarins and Related Compounds

Natural Product Communications, 2018
Fifty natural and synthetic hydroxy-, aminohydroxynaphthazarins and related quinones were tested for their antiradical activities using 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) scavenging assay.
Nikita S. Polonik, Yuri E. Sabutskii, Sergey G. Polonik   +2 more
doaj   +1 more source

Separation and identification of menaquinones irom microorganisms

Journal of Lipid Research, 1971
Simple thin-layer chromatographic procedures are outlined for the separation, isolation, and characterization of a complex of lipophilic naphthoquinones.
PATRICK J. DUNPHY, PHILIP G. PHILLIPS, ARNOLD F. BRODIE   +2 more
doaj   +1 more source

Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits

Journal of Tropical Medicine, 2017
A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the ...
Tatiane Freitas Borgati, Maria Fernanda Alves do Nascimento, Juma Fortunato Bernardino, Lunamaura Claudia Oliveira Martins, Alex Gutterres Taranto, Alaíde Braga de Oliveira   +5 more
doaj   +1 more source

Synthesis of branched naphthoquinones from castor oil

Orbital: The Electronic Journal of Chemistry, 2012
The naphthoquinones are cyclic aromatic α,β-dienonas with a basic framework derived from naphthalene. They are also found in many higher plants, algae, fungi and as the product of the  metabolism  of some  bacteria  having large biologica activity ...
Adriano Olímpio da Silva, Dênis P. de Lima, Rosangela da Silva Lopes, Ricardo Vieira de Lima, Roberto da Silva Gomes   +4 more
doaj   +1 more source

Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples

Sensors, 2006
Naphthoquinones are one of the groups of secondary metabolites widespread innature, where they mostly appear as chromatic pigments. They embody broad-range ofbiological actions from phytotoxic to fungicidal.
Rene Kizek, Miroslava Beklova, Ales Horna, Milan Zemlicka, Ladislav Havel, Jaromir Hubalek, Vojtech Adam, Sona Krizkova, Jiri Baloun, Pavel Hanustiak, Dalibor Huska, Petr Babula   +11 more
doaj   +1 more source

Enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes catalyzed by binaphthyl-derived organocatalysts

Beilstein Journal of Organic Chemistry, 2012
The highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes, promoted by binaphthyl-modified chiral bifunctional organocatalysts is described.
Saet Byeol Woo, Dae Young Kim
doaj   +1 more source

Is nitric oxide decrease observed with naphthoquinones in LPS stimulated RAW 264.7 macrophages a beneficial property? [PDF]

PLoS ONE, 2011
The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays.
Brígida R Pinho, Carla Sousa, Patrícia Valentão, Paula B Andrade   +3 more
doaj   +1 more source

Pro-Apoptotic Antitumoral Effect of Novel Acridine-Core Naphthoquinone Compounds against Oral Squamous Cell Carcinoma

Molecules, 2022
Oral squamous cell carcinoma (OSCC) is a global public health problem with high incidence and mortality. The chemotherapeutic agents used in the clinic, alone or in combination, usually lead to important side effects.
Bruna Costa Zorzanelli, Gabriel Ouverney, Fernanda P. Pauli, Anna Carolina Carvalho da Fonseca, Elan Cardozo Paes de Almeida, Danielle Gonçalves de Carvalho, Patricia Abrão Possik, Vitor Won-Held Rabelo, Paula Alvarez Abreu, Bruno Pontes, Vitor Francisco Ferreira, Luana da Silva Magalhães Forezi, Fernando de Carvalho da Silva, Bruno Kaufmann Robbs   +13 more
doaj   +1 more source

Shikonin and Juglone Inhibit Mycobacterium tuberculosis Low-Molecular-Weight Protein Tyrosine Phosphatase a (Mt-PTPa)

BioTech, 2023
Low-molecular-weight protein tyrosine phosphatases (LMW-PTPs) are involved in promoting the intracellular survival of Mycobacterium tuberculosis (Mtb), the causative organism of tuberculosis.
Abdulhakeem O. Sulyman, Jessie Fulcher, Samuel Crossley, Amos A. Fatokun, Femi J. Olorunniji   +4 more
doaj   +1 more source

Photogrammetry of Ultrafast Excited-State Intramolecular Proton Transfer Pathways in the Fungal Pigment Draconin Red

Molecules, 2023
Proton transfer processes of organic molecules are key to charge transport and photoprotection in biological systems. Among them, excited-state intramolecular proton transfer (ESIPT) reactions are characterized by quick and efficient charge transfer ...
Janak Solaris, Taylor D. Krueger, Cheng Chen, Chong Fang   +3 more
doaj   +1 more source