Results 21 to 30 of about 11,091 (232)
ATP acts in the extracellular environment as an important signal, activating a family of receptors called purinergic receptors. In recent years, interest in the potential therapeutics of purinergic components, including agonists and antagonists of ...
Paulo Anastácio Furtado Pacheco +7 more
doaj +1 more source
Unique biosynthetic abilities revealed by plants determine in vitro cultures of hairy roots as a suitable source of pharmaceutically relevant bioactive compounds.
Bartosz Nowak +4 more
doaj +1 more source
Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite [PDF]
The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described.
Herscheid, Jacobus D.M. +3 more
core +3 more sources
Different extracts and isolated substances from the root of Onosma visianii Clem. as antifungal agents [PDF]
The aim of this study was to determine the antifungal activity of extracts and isolated substances from the root of Onosma visianii Clem. (Boraginaceae) by determining the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC).
Radojević Ivana D. +4 more
doaj
Some plant species are less susceptible to herbivore infestation than others. The reason for this is often unknown in detail but is very likely due to an efficient composition of secondary plant metabolites.
Asifur Rahman-Soad +3 more
doaj +1 more source
POLYPHENOLS AND NAPHTHOQUINONES EXTRACTION FROM WALNUTS PELLICULA: THE IMPACT ON KERNELS QUALITY [PDF]
Walnuts change their appearance during storage, becoming brown and bitter. The aim of this paper was to determine the polyphenols and naphthoquinones extraction process parameters from the pellicle of kernels, and to assess the influence of extraction on
Baerle, Alexei +2 more
doaj +1 more source
Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment
Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects, TB/HIV co-infection and the emergence of resistant Mycobacterium tuberculosis strains.
Priscila C. B. Halicki +8 more
doaj +1 more source
Activity of Some Plant and Fungal Metabolites towards Aedes albopictus (Diptera, Culicidae)
Aedes albopictus (Skuse) is a widespread mosquito, a vector of important human arboviruses, including Chikungunya, Dengue and Zika. It is an extremely difficult species to control even for the onset of resistances to chemicals insecticides, therefore ...
Sonia Ganassi +4 more
doaj +1 more source
Machine Learning Accelerates Crystallization for Structure Determination
Single‐crystal x‐ray diffraction (SCXRD) is often constrained by the difficulty of obtaining suitable crystals. Here, a machine learning‐accelerated co‐crystal discovery workflow is established for a crystalline mate strategy that achieves over 95% prediction accuracy and experimentally delivers 114 co‐crystals from 120 candidates.
Cui‐Zhou Luan +10 more
wiley +2 more sources
Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core +1 more source

