Results 21 to 30 of about 6,879 (216)

Biomimetic Synthesis of Antimalarial Naphthoquinones [PDF]

Journal of the American Chemical Society, 2005
The total synthesis of naphthoquinone natural products isolated from the Bignoniaceae plant family is described. Pinnatal, isopinnatal, sterekunthals A and B, pyranokunthones A and B, and anthrakunthone have been prepared along the lines of a biosynthetic proposal involving pericyclic reactions as key steps.
Jeremiah P, Malerich, Thomas J, Maimone, Gregory I, Elliott, Dirk, Trauner   +3 more
openaire   +3 more sources

MTMS-Based Aerogel Constructs for Immobilization of Plant Hairy Roots: Effects on Proliferation of Rindera graeca Biomass and Extracellular Secretion of Naphthoquinones

Journal of Functional Biomaterials, 2021
Unique biosynthetic abilities revealed by plants determine in vitro cultures of hairy roots as a suitable source of pharmaceutically relevant bioactive compounds.
Bartosz Nowak, Mateusz Kawka, Kamil Wierzchowski, Katarzyna Sykłowska-Baranek, Maciej Pilarek   +4 more
doaj   +1 more source

Different extracts and isolated substances from the root of Onosma visianii Clem. as antifungal agents [PDF]

Kragujevac Journal of Science, 2023
The aim of this study was to determine the antifungal activity of extracts and isolated substances from the root of Onosma visianii Clem. (Boraginaceae) by determining the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC).
Radojević Ivana D., Marković Katarina G., Grujović Mirjana Ž., Vukić Milena D., Vuković Nenad L.   +4 more
doaj  

Plumbagin, a Potent Naphthoquinone from Nepenthes Plants with Growth Inhibiting and Larvicidal Activities

Molecules, 2021
Some plant species are less susceptible to herbivore infestation than others. The reason for this is often unknown in detail but is very likely due to an efficient composition of secondary plant metabolites.
Asifur Rahman-Soad, Alberto Dávila-Lara, Christian Paetz, Axel Mithöfer   +3 more
doaj   +1 more source

Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Frontiers in Microbiology, 2018
Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects, TB/HIV co-infection and the emergence of resistant Mycobacterium tuberculosis strains.
Priscila C. B. Halicki, Laís A. Ferreira, Kelly C. G. De Moura, Paula F. Carneiro, Karina P. Del Rio, Tatiane dos S. C. Carvalho, Maria do C. F. R. Pinto, Pedro E. A. da Silva, Daniela F. Ramos   +8 more
doaj   +1 more source

Activity of Some Plant and Fungal Metabolites towards Aedes albopictus (Diptera, Culicidae)

Toxins, 2021
Aedes albopictus (Skuse) is a widespread mosquito, a vector of important human arboviruses, including Chikungunya, Dengue and Zika. It is an extremely difficult species to control even for the onset of resistances to chemicals insecticides, therefore ...
Sonia Ganassi, Marco Masi, Pasqualina Grazioso, Antonio Evidente, Antonio De Cristofaro   +4 more
doaj   +1 more source

Free Radical Scavenging Activity of Synthetic and Naturally Occurring Polyhydroxy-, Aminohydroxynaphthazarins and Related Compounds

Natural Product Communications, 2018
Fifty natural and synthetic hydroxy-, aminohydroxynaphthazarins and related quinones were tested for their antiradical activities using 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) scavenging assay.
Nikita S. Polonik, Yuri E. Sabutskii, Sergey G. Polonik   +2 more
doaj   +1 more source

Separation and identification of menaquinones irom microorganisms

Journal of Lipid Research, 1971
Simple thin-layer chromatographic procedures are outlined for the separation, isolation, and characterization of a complex of lipophilic naphthoquinones.
PATRICK J. DUNPHY, PHILIP G. PHILLIPS, ARNOLD F. BRODIE   +2 more
doaj   +1 more source

Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits

Journal of Tropical Medicine, 2017
A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the ...
Tatiane Freitas Borgati, Maria Fernanda Alves do Nascimento, Juma Fortunato Bernardino, Lunamaura Claudia Oliveira Martins, Alex Gutterres Taranto, Alaíde Braga de Oliveira   +5 more
doaj   +1 more source

Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples

Sensors, 2006
Naphthoquinones are one of the groups of secondary metabolites widespread innature, where they mostly appear as chromatic pigments. They embody broad-range ofbiological actions from phytotoxic to fungicidal.
Rene Kizek, Miroslava Beklova, Ales Horna, Milan Zemlicka, Ladislav Havel, Jaromir Hubalek, Vojtech Adam, Sona Krizkova, Jiri Baloun, Pavel Hanustiak, Dalibor Huska, Petr Babula   +11 more
doaj   +1 more source