Results 41 to 50 of about 84,320 (339)

ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation [PDF]

Circulation Research, 2014
Although recent genome-wide association studies have called into question the causal relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular disease, ongoing research in animals and cells has produced increasing evidence that cholesterol efflux pathways mediated by ATP-binding cassette (ABC) transporters and HDL ...
Marit, Westerterp, Andrea E, Bochem, Laurent, Yvan-Charvet, Andrew J, Murphy, Nan, Wang, Alan R, Tall   +5 more
openaire   +5 more sources

An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein [PDF]

, 2005
Campylobacter jejuni is a Gram-negative food-borne pathogen associated with gastroenteritis in humans as well as cases of the autoimmune disease Guillain Barre syndrome. C.
Altekruse, Anthony J. Wilkinson, Axel Müller, Brown, Bryant, Burguiere, Deka, Delaney, During-Olsen, Elena Blagova, Emsley, Fukami-Kobayashi, Gavin H. Thomas, Gouet, Harris, Holland, Hosie, Hosie, James A. Brannigan, Jones, Kaldor, Kazwala, Keith S. Wilson, Kelly, Kertesz, Kraulis, Levdikov, Magnusson, Mark J. Fogg, Martin, Merrell, Merritt, Miller, Murshudov, Newberry, Newcomer, Oh, Oh, Olsen, Palmer, Parkhill, Pawelec, Pawelec, Pei, Pei, Perrakis, Pittman, Richard Horler, Rosef, Schonheyder, Sun, Svedhem, Takahashi, Terwilliger, Vagin, Vargas, Velayudhan, Vladimir M. Levdikov, Walter, Wilkinson, Wyszynska, Yao   +61 more
core   +1 more source

The E. coli BtuCD Structure: A Framework for ABC Transporter Architecture and Mechanism [PDF]

, 2002
The ABC transporters are ubiquitous membrane proteins that couple adenosine triphosphate (ATP) hydrolysis to the translocation of diverse substrates across cell membranes.
Lee, Allen T., Locher, Kaspar P., Rees, Douglas C.   +2 more
core   +1 more source

Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

Microorganisms, 2021
ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as ...
Jeanine Rismondo, Lisa Maria Schulz
doaj   +1 more source

Twenty years of ATP-binding cassette (ABC) transporters [PDF]

Pflügers Archiv - European Journal of Physiology, 2018
ATP-binding cassette (ABC) transporters constitute a large superfamily of primary active transport systems, which play a diversity of physiological roles, and are found in all cells of all kingdoms [3]. The year 2006 marks the 20th anniversary of the identification of this superfamily of proteins in 1986 [4].
Higgins, Christopher, Stieger, Bruno
core   +4 more sources

Peptides and ATP binding cassette peptide transporters [PDF]

Research in Microbiology, 2001
In this review our knowledge of ATP binding cassette (ABC) transporters specific for peptides is discussed. Besides serving a role in nutrition of the cell, the systems participate in various signaling processes that allow (micro)organisms to monitor the local environment. In bacteria, these include regulation of gene expression, competence development,
Detmers, F.J.M., Lanfermeijer, F.C., Poolman, B.   +2 more
openaire   +4 more sources

Biological Functions and Clinical Significance of the ABCG1 Transporter

Biology
ATP-binding cassette (ABC) transporters are a large family of proteins that transport various substances across cell membranes using energy from ATP hydrolysis.
Stanislav Kotlyarov, Anna Kotlyarova
doaj   +1 more source

A Case Report of Dyschromatosis Universalis Hereditaria (DUH) with Primary Ovarian Failure (POF) [PDF]

Journal of Clinical and Diagnostic Research, 2016
Dyschromatosis Universalis Hereditaria (DUH) belongs to a group of congenital diffuse reticulate pigmentary disorders characterised by both hypo and hyper pigmented macules. It is both hereditary and sporadic.
N.S Jayanthi, V. Anandan, W. Afthab Jameela, V. Senthil Kumar, P. Lavanya   +4 more
doaj   +1 more source

Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]

, 2014
Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain, Hayashida, Minaho, Ito, Shingo, Minami, Shota, Morita, Masahiko, Moriyama, Yoshinori, Moriyasu, Masataka, Omote, Hiroshi, Shitan, Nobukazu, Sugiyama, Akifumi, Takanashi, Kojiro, Yazaki, Kazufumi   +11 more
core   +8 more sources

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

eLife, 2014
Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the
Smriti Mishra, Brandy Verhalen, Richard A Stein, Po-Chao Wen, Emad Tajkhorshid, Hassane S Mchaourab   +5 more
doaj   +1 more source