Results 21 to 30 of about 1,686,547 (237)
Nucleotide-Binding Sites of the Heterodimeric LmrCD ABC-Multidrug Transporter of Lactococcus lactis Are Asymmetric [PDF]
, 2006 LmrCD is a lactococcal, heterodimeric multidrug transporter, which belongs to the ABC superfamily. It consists of two half-transporters, LmrC and LmrD, that are necessary and sufficient for drug extrusion and ATP hydrolysis.
Konings, Wil N. +7 more
core +2 more sources
Cardiac PET Imaging of ATP Binding Cassette (ABC) Transporters: Opportunities and Challenges
Pharmaceuticals, 2023 Adenosine triphosphate binding cassette (ABC) transporters are a broad family of membrane protein complexes that use energy to transport molecules across cells and/or intracellular organelle lipid membranes. Many drugs used to treat cardiac diseases have
Wanling Liu +4 more
doaj +1 more source
Role of ABCG1 and other ABCG family members in lipid metabolism
Journal of Lipid Research, 2001 The molecular cloning and identification of mutations in ATP-binding cassette transporters in hereditary diseases have greatly expanded our knowledge of the normal physiology of intracellular lipid transport processes.
Gerd Schmitz +2 more
doaj +1 more source
eLife, 2020 ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters, responsible for many physiological processes and human maladies.
Erich Stefan +2 more
doaj +1 more source
ATP-binding cassette (ABC) transporters in normal and pathological lung
Respiratory Research, 2005 ATP-binding cassette (ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner.
Timmer-Bosscha Hetty +5 more
doaj +1 more source
Jadomycins: A potential chemotherapy for multi‐drug resistant metastatic breast cancer
Pharmacology Research & Perspectives, 2021 Breast cancer causes the most cancer fatalities in women worldwide. Approximately one‐third of breast cancers metastasize, or spread from primary tumors to other tissues, and have a 70% 5‐year mortality rate.
Esther P. Bonitto +2 more
doaj +1 more source
Coupled ATPase-adenylate kinase activity in ABC transporters
Nature Communications, 2016 ATP-binding cassette (ABC) transporters hydrolyse ATP to transport molecules across the cell membrane. Here Vogelet al. show that the ABC exporter MsBA can couple ATP hydrolyse to an adenylate kinase activity that seems to be predominant at low ATP ...
Hundeep Kaur +5 more
doaj +1 more source
Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato.
PLoS ONE, 2018 ATP binding cassette (ABC) transporters are proteins that actively mediate the transport of a wide range of molecules, such as organic acids, metal ions, phytohormones and secondary metabolites.
Peter Amoako Ofori +9 more
doaj +1 more source
Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies
Communications Biology, 2021 Zhang et al. present the cryo-EM structure of ATP-binding cassette transporters ABCG5/G8 in complex with the Fab fragments from two monoclonal antibodies at 3.3 Å resolution.
Hanzhi Zhang +8 more
doaj +1 more source
Transcriptional and post-transcriptional regulation of ATP-binding cassette transporters.
, 2004 Transcriptional and post-transcriptional regulation of ATP-binding cassette ...
Pui Lai Rachel. Ee (7996370)
core +6 more sources