Results 21 to 30 of about 50,926 (288)
Increased expression of ATP‐binding cassette transporters in enfortumab vedotin‐resistant urothelial cancer [PDF]
IJU Case ReportsIntroduction In addition to reduced nectin‐4 expression, the upregulation of ATP‐binding cassette transporters has been suggested as a potential mechanism of resistance to enfortumab vedotin.
Mariko Kotono +9 more
doaj +2 more sources
ATP-binding cassette transporters in Escherichia coli
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2008 ATP-binding cassette (ABC) transporters are integral membrane proteins that actively transport molecules across cell membranes. In Escherichia coli they consist primarily of import systems that involve in addition to the ABC transporter itself a substrate binding protein and outer membrane receptors or porins, and a number of transporters with varied ...
Moussatova, Anastassiia +3 more
openaire +6 more sources
ATP-binding cassette (ABC) transporters in normal and pathological lung [PDF]
Respiratory Research, 2005 ATP-binding cassette (ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner.
Timmer-Bosscha Hetty +5 more
doaj +2 more sources
Structural View of Cryo-Electron Microscopy-Determined ATP-Binding Cassette Transporters in Human Multidrug Resistance [PDF]
BiomoleculesATP-binding cassette (ABC) transporters, acting as cellular “pumps,” facilitate solute translocation through membranes via ATP hydrolysis. Their overexpression is closely tied to multidrug resistance (MDR), a major obstacle in chemotherapy and ...
Wenjie Fan, Kai Shao, Min Luo
doaj +2 more sources
ATP-binding cassette transporters and drug resistance in cutaneous leishmaniasis
International Journal of Infectious DiseasesLeishmania spp. are intracellular protozoan parasites causative of visceral and cutaneous leishmaniasis. Recognized as a neglected tropical disease affecting millions of people around the world, this affliction represents a major public health problem ...
Marina B.R. de Santana +2 more
doaj +2 more sources
ATP-binding cassette transporters in reproduction: a new frontier. [PDF]
Hum Reprod Update, 2016 The transmembrane ATP-binding cassette (ABC) transporters actively efflux an array of clinically relevant compounds across biological barriers, and modulate biodistribution of many physiological and pharmacological factors. To date, over 48 ABC transporters have been identified and shown to be directly and indirectly involved in peri-implantation ...
Bloise E +5 more
europepmc +4 more sources
Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages [PDF]
Molecules, 2018 Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages.
I-Jou Teng +8 more
doaj +2 more sources
ATP‐binding cassette transporters in nonmodel plants [PDF]
New Phytologist, 2021 SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
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AMB Express, 2022 Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner +3 more
doaj +1 more source
ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation [PDF]
Circulation Research, 2014 Although recent genome-wide association studies have called into question the causal relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular disease, ongoing research in animals and cells has produced increasing evidence that cholesterol efflux pathways mediated by ATP-binding cassette (ABC) transporters and HDL ...
Marit, Westerterp +5 more
openaire +5 more sources