Results 11 to 20 of about 46,561 (242)

Cadmium transport by mammalian ATP-binding cassette transporters. [PDF]

Biometals
AbstractCellular responses to toxic metals depend on metal accessibility to intracellular targets, reaching interaction sites, and the intracellular metal concentration, which is mainly determined by uptake pathways, binding/sequestration and efflux pathways.
Thévenod F, Lee WK.
europepmc   +4 more sources

ATP-Binding Cassette Transporters in the Clinical Implementation of Pharmacogenetics [PDF]

Journal of Personalized Medicine, 2018
Luis A López-Fernández
exaly   +2 more sources

ATP‐binding cassette transporters in nonmodel plants [PDF]

New Phytologist, 2021
SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
openaire   +2 more sources

Transcriptome profiling of Paraburkholderia aromaticivorans AR20-38 during ferulic acid bioconversion

AMB Express, 2022
Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner, Thomas Marek Ludwikowski, Andreas Otto Wagner, Rosa Margesin   +3 more
doaj   +1 more source

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

Frontiers in Pharmacology, 2023
Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato, Tatsuya Seki, Asuka Mizutani, Yuka Muranaka, Shiho Hirota, Kodai Nishi, Kana Yamazaki, Ryuichi Nishii, Takeo Nakanishi, Ikumi Tamai, Keiichi Kawai, Keiichi Kawai, Masato Kobayashi   +12 more
doaj   +1 more source

De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

eLife, 2021
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan, Richard Obexer, Susanne Hofmann, Khanh Vu Huu, Yichao Huang, Nina Morgner, Hiroaki Suga, Robert Tampé   +7 more
doaj   +1 more source

Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2

Technology in Cancer Research & Treatment, 2020
The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma.
Yan Song MD, Ning Hu MD, Xiaowei Song MD, Juhong Yang MD   +3 more
doaj   +1 more source

The Mechanisms of Yu Ping Feng San in Tracking the Cisplatin-Resistance by Regulating ATP-Binding Cassette Transporter and Glutathione S-Transferase in Lung Cancer Cells

Frontiers in Pharmacology, 2021
Cisplatin is one of the first line anti-cancer drugs prescribed for treatment of solid tumors; however, the chemotherapeutic drug resistance is still a major obstacle of cisplatin in treating cancers. Yu Ping Feng San (YPFS), a well-known ancient Chinese
Yingqing Du, Yuzhong Zheng, Ciel Xiaomei Yu, Lishan Zhong, Yafang Li, Baomeng Wu, Weihui Hu, Elsa Wanyi Zhu, Venus Wei Xie, Qitian Xu, Xingri Zhan, Yamiao Huang, Liyi Zeng, Zhenxia Zhang, Xi Liu, Jiachuan Yin, Guangcai Zha, Kelvin Chan, Kelvin Chan, Karl Wah Keung Tsim   +19 more
doaj   +1 more source

ATP Binding Cassette transporters associated with chemoresistance: transcriptional profiling in extreme cohorts and their prognostic impact in a cohort of 281 acute myeloid leukemia patients

Haematologica, 2011
Background A major issue in the treatment of acute myeloid leukemia is resistance to chemotherapeutic drugs. An increasing number of ATP-Binding-Cassette transporters have been demonstrated to cause resistance to cancer drugs.
Christophe Marzac, Edith Garrido, Ruoping Tang, Fanny Fava, Pierre Hirsch, Cinzia De Benedictis, Elise Corre, Simona Lapusan, Jean-Yves Lallemand, Jean-Pierre Marie, Eric Jacquet, Ollivier Legrand   +11 more
doaj   +1 more source

ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation [PDF]

Circulation Research, 2014
Although recent genome-wide association studies have called into question the causal relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular disease, ongoing research in animals and cells has produced increasing evidence that cholesterol efflux pathways mediated by ATP-binding cassette (ABC) transporters and HDL ...
Marit, Westerterp, Andrea E, Bochem, Laurent, Yvan-Charvet, Andrew J, Murphy, Nan, Wang, Alan R, Tall   +5 more
openaire   +5 more sources