Results 11 to 20 of about 1,686,547 (237)

Transport and catabolism of murein tripeptide in Escherichia coli K-12 [PDF]

, 2011
In bacteria, extracellular peptides are not only a source of nutrients but also play important roles in cell-cell communication. The primary mode of uptake of these peptides in bacteria is via ATP Binding Cassette (ABC) transporters.
Maqbool, Abbas
core   +6 more sources

Investigation of the Function and Regulation of ABC Transporters [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorATP-Binding-Cassette (ABC) transporters are primary active pumps that typically ...
Akkaya, Begum Gokcen
core   +4 more sources

Transcriptome profiling of Paraburkholderia aromaticivorans AR20-38 during ferulic acid bioconversion

AMB Express, 2022
Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner, Thomas Marek Ludwikowski, Andreas Otto Wagner, Rosa Margesin   +3 more
doaj   +1 more source

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

Frontiers in Pharmacology, 2023
Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato, Tatsuya Seki, Asuka Mizutani, Yuka Muranaka, Shiho Hirota, Kodai Nishi, Kana Yamazaki, Ryuichi Nishii, Takeo Nakanishi, Ikumi Tamai, Keiichi Kawai, Keiichi Kawai, Masato Kobayashi   +12 more
doaj   +1 more source

De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

eLife, 2021
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan, Richard Obexer, Susanne Hofmann, Khanh Vu Huu, Yichao Huang, Nina Morgner, Hiroaki Suga, Robert Tampé   +7 more
doaj   +1 more source

Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2

Technology in Cancer Research & Treatment, 2020
The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma.
Yan Song MD, Ning Hu MD, Xiaowei Song MD, Juhong Yang MD   +3 more
doaj   +1 more source

The Mechanisms of Yu Ping Feng San in Tracking the Cisplatin-Resistance by Regulating ATP-Binding Cassette Transporter and Glutathione S-Transferase in Lung Cancer Cells

Frontiers in Pharmacology, 2021
Cisplatin is one of the first line anti-cancer drugs prescribed for treatment of solid tumors; however, the chemotherapeutic drug resistance is still a major obstacle of cisplatin in treating cancers. Yu Ping Feng San (YPFS), a well-known ancient Chinese
Yingqing Du, Yuzhong Zheng, Ciel Xiaomei Yu, Lishan Zhong, Yafang Li, Baomeng Wu, Weihui Hu, Elsa Wanyi Zhu, Venus Wei Xie, Qitian Xu, Xingri Zhan, Yamiao Huang, Liyi Zeng, Zhenxia Zhang, Xi Liu, Jiachuan Yin, Guangcai Zha, Kelvin Chan, Kelvin Chan, Karl Wah Keung Tsim   +19 more
doaj   +1 more source

Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]

, 2006
ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Schuurman-Wolters, Gea,, Pretz, Monika G., Tampé, Robert,, van der Does, Chris, Driessen, Arnold J. M., Albers, Sonja-Verena,, Tampe, Robert, Does, Chris van der,, Albers, Sonja-Verena, Schuurman-Wolters, Gea; id_orcid, Pretz, Monika G.,, Albers, Sonja Verena, Does, Chris van der, Schuurman-Wolters, Gea, Driessen, Arnold J.M.,   +14 more
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ATP Binding Cassette transporters associated with chemoresistance: transcriptional profiling in extreme cohorts and their prognostic impact in a cohort of 281 acute myeloid leukemia patients

Haematologica, 2011
Background A major issue in the treatment of acute myeloid leukemia is resistance to chemotherapeutic drugs. An increasing number of ATP-Binding-Cassette transporters have been demonstrated to cause resistance to cancer drugs.
Christophe Marzac, Edith Garrido, Ruoping Tang, Fanny Fava, Pierre Hirsch, Cinzia De Benedictis, Elise Corre, Simona Lapusan, Jean-Yves Lallemand, Jean-Pierre Marie, Eric Jacquet, Ollivier Legrand   +11 more
doaj   +1 more source

Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and in HuH7 cells. [PDF]

, 2013
Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through ...
Enrich Bastús, Carles, Enrich Carlos, Karen Cecilia Chan, Monira Hoque, Darabi, Masoud, Reverter Martín, Meritxell, Hoque, Monira, Rentero Alfonso, Carles, Meritxell Reverter, Rentero Carles, Melanie Manetsch, Masoud Darabi, Mulay, Vishwaroop, Peta Wood, Grewal Thomas, Álvarez-Guaita, Anna, Heeren, Joerg, Anna Alvarez-Guaita, Kerry-Anne Rye, Darabi Masoud, Rye Kerry-Anne, Chan, Karen Cecilia, Manetsch, Melanie, Mulay Vishwaroop, Manetsch Melanie, Heeren Joerg, Carlos Enrich, Cairns, Rose, Reverter Meritxell, Joerg Heeren, Carles Rentero, Vishwaroop Mulay, Rose Cairns, Wood Peta, Wood, Peta, Grewal, Thomas, Rye, Kerry-Anne, Chan Karen Cecilia, Álvarez-Guaita Anna, Thomas Grewal, Hoque Monira, Cairns Rose   +41 more
core   +2 more sources