Results 11 to 20 of about 82,308 (291)

ECF-Type ATP-Binding Cassette Transporters [PDF]

open access: yesAnnual Review of Biochemistry, 2019
Energy-coupling factor (ECF)–type ATP-binding cassette (ABC) transporters catalyze membrane transport of micronutrients in prokaryotes. Crystal structures and biochemical characterization have revealed that ECF transporters are mechanistically distinct from other ABC transport systems.
Rempel, S, Stanek, W K, Slotboom, D J
openaire   +4 more sources

ABC transporters: the power to change [PDF]

open access: yesNature Reviews Molecular Cell Biology, 2009
ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered translocation of many substrates across membranes.
Johnson, Eric   +2 more
core   +5 more sources

Peroxisomal ATP-binding cassette transporters form mainly tetramers. [PDF]

open access: yesJ Biol Chem, 2017
ABCD1 and its homolog ABCD2 are peroxisomal ATP-binding cassette (ABC) half-transporters of fatty acyl-CoAs with both distinct and overlapping substrate specificities. Although it is established that ABC half-transporters have at least to dimerize to generate a functional unit, functional equivalents of tetramers (i.e.
Geillon F   +10 more
europepmc   +5 more sources

Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages [PDF]

open access: yesMolecules, 2018
Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages.
I-Jou Teng   +8 more
doaj   +2 more sources

Nucleotide-Binding Sites of the Heterodimeric LmrCD ABC-Multidrug Transporter of Lactococcus lactis Are Asymmetric [PDF]

open access: yes, 2006
LmrCD is a lactococcal, heterodimeric multidrug transporter, which belongs to the ABC superfamily. It consists of two half-transporters, LmrC and LmrD, that are necessary and sufficient for drug extrusion and ATP hydrolysis.
Driessen, Arnold J.M.,   +3 more
core   +19 more sources

Transcriptome profiling of Paraburkholderia aromaticivorans AR20-38 during ferulic acid bioconversion

open access: yesAMB Express, 2022
Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner   +3 more
doaj   +1 more source

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

open access: yesFrontiers in Pharmacology, 2023
Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato   +12 more
doaj   +1 more source

De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

open access: yeseLife, 2021
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan   +7 more
doaj   +1 more source

Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2

open access: yesTechnology in Cancer Research & Treatment, 2020
The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma.
Yan Song MD   +3 more
doaj   +1 more source

ATP‐binding cassette transporters in nonmodel plants [PDF]

open access: yesNew Phytologist, 2021
SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
openaire   +2 more sources

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