Structure and function of the bacterial heterodimeric ABC transporter CydDC: stimulation of ATPase activity by thiol and heme compounds. [PDF]
, 2014 In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ATP-binding cassette-type cysteine/GSH transporter, CydDC.
Baldwin, SA +9 more
core +3 more sources
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome [PDF]
, 2009 Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-1 beta (IL-1 beta) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes triggered by microbial ligands, danger-associated molecular patterns
Mohamed Lamkanfi +43 more
core +2 more sources
Microorganisms, 2021 ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as ...
Jeanine Rismondo, Lisa Maria Schulz
doaj +1 more source
Peptides and ATP binding cassette peptide transporters [PDF]
Research in Microbiology, 2001 In this review our knowledge of ATP binding cassette (ABC) transporters specific for peptides is discussed. Besides serving a role in nutrition of the cell, the systems participate in various signaling processes that allow (micro)organisms to monitor the local environment. In bacteria, these include regulation of gene expression, competence development,
Detmers, F.J.M. +2 more
openaire +4 more sources
Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins [PDF]
, 2017 The development of drug resistance continues to be a dominant hindrance toward curative cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and in particular of ABCB1 (P-glycoprotein or MDR1) is a well-known resistance ...
Assaraf, Yehuda G. +4 more
core +1 more source
Biological Functions and Clinical Significance of the ABCG1 Transporter
BiologyATP-binding cassette (ABC) transporters are a large family of proteins that transport various substances across cell membranes using energy from ATP hydrolysis.
Stanislav Kotlyarov, Anna Kotlyarova
doaj +1 more source
A Case Report of Dyschromatosis Universalis Hereditaria (DUH) with Primary Ovarian Failure (POF) [PDF]
Journal of Clinical and Diagnostic Research, 2016 Dyschromatosis Universalis Hereditaria (DUH) belongs to a group of congenital diffuse reticulate pigmentary disorders characterised by both hypo and hyper pigmented macules. It is both hereditary and sporadic.
N.S Jayanthi +4 more
doaj +1 more source
A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex formation [PDF]
, 2010 ATP-binding cassette (ABC) transporters are integral membrane proteins that translocate a diverse array of substrates across cell membranes. We present here the dynamics of complex formation of three structurally characterized ABC transporters—the BtuCD ...
Lee, Allen T. +3 more
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RNAseq reveals hydrophobins that are involved in the adaptation of aspergillus nidulans to lignocellulose [PDF]
, 2016 Background Sugarcane is one of the world’s most profitable crops. Waste steam-exploded sugarcane bagasse (SEB) is a cheap, abundant, and renewable lignocellulosic feedstock for the next-generation biofuels.
Brown, Neil Andrew +7 more
core +4 more sources
eLife, 2014 Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the
Smriti Mishra +5 more
doaj +1 more source