Results 41 to 50 of about 50,926 (288)

Jadomycins: A potential chemotherapy for multi‐drug resistant metastatic breast cancer

Pharmacology Research & Perspectives, 2021
Breast cancer causes the most cancer fatalities in women worldwide. Approximately one‐third of breast cancers metastasize, or spread from primary tumors to other tissues, and have a 70% 5‐year mortality rate.
Esther P. Bonitto, Brendan T. McKeown, Kerry B. Goralski   +2 more
doaj   +1 more source

Coupled ATPase-adenylate kinase activity in ABC transporters

Nature Communications, 2016
ATP-binding cassette (ABC) transporters hydrolyse ATP to transport molecules across the cell membrane. Here Vogelet al. show that the ABC exporter MsBA can couple ATP hydrolyse to an adenylate kinase activity that seems to be predominant at low ATP ...
Hundeep Kaur, Andrea Lakatos-Karoly, Ramona Vogel, Anne Nöll, Robert Tampé, Clemens Glaubitz   +5 more
doaj   +1 more source

Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato.

PLoS ONE, 2018
ATP binding cassette (ABC) transporters are proteins that actively mediate the transport of a wide range of molecules, such as organic acids, metal ions, phytohormones and secondary metabolites.
Peter Amoako Ofori, Ayaka Mizuno, Mami Suzuki, Enrico Martinoia, Stefan Reuscher, Koh Aoki, Daisuke Shibata, Shungo Otagaki, Shogo Matsumoto, Katsuhiro Shiratake   +9 more
doaj   +1 more source

ABC transporters in Dictyostelium discoideum development [PDF]

, 2013
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins.
Adam Kuspa, Gad Shaulsky (10030), Toplak Marko, Balaji Santhanam, Zhuchenko Olga, Adam Kuspa (45348), Marko Toplak, Gad Shaulsky, Shaulsky, Gad, Miranda Edward Roshan, Balaji Santhanam (155206), Zupan Blaz, Santhanam, Balaji, Kuspa Adam, Zupan, Blaz, Edward Roshan Miranda (446004), Marko Toplak (446006), Zhuchenko, Olga, Edward Roshan Miranda, Blaz Zupan (10031), Miranda, Edward Roshan, Olga Zhuchenko, Kuspa, Adam, Blaz Zupan, Olga Zhuchenko (446005), Santhanam Balaji, Shaulsky Gad, Toplak, Marko   +27 more
core   +1 more source

ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei [PDF]

, 2007
© 2007 Harland et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Brown, Katherine A., Elie Dassa, Katherine A Brown, Titball, Richard W., Brown Katherine A, Titball, Richard W, Helen S Atkins, Harland, David N., Richard W Titball, Atkins Helen S, Brown, Katherine A, David N Harland, Atkins, Helen S., Dassa Elie, Harland, David N, Titball Richard W, Dassa, Elie, Harland David N, Atkins, Helen S   +18 more
core   +1 more source

Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies

Communications Biology, 2021
Zhang et al. present the cryo-EM structure of ATP-binding cassette transporters ABCG5/G8 in complex with the Fab fragments from two monoclonal antibodies at 3.3 Å resolution.
Hanzhi Zhang, Ching-Shin Huang, Xinchao Yu, Jonas Lee, Amit Vaish, Qing Chen, Mingyue Zhou, Zhulun Wang, Xiaoshan Min   +8 more
doaj   +1 more source

The Human ATP-Binding Cassette (ABC) Transporter Superfamily [PDF]

Genome Research, 2001
The ATP-binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra- and intra-cellular membranes. Mutations in ABC genes cause 21 human disorders or phenotypes with Mendelian inheritance, including cystic fibrosis, adrenoleukodystrophy, retinal degeneration, cholesterol, and bile ...
Michael Dean, Karobi Moitra, Rando Allikmets   +2 more
openaire   +3 more sources

A Case Report of Dyschromatosis Universalis Hereditaria (DUH) with Primary Ovarian Failure (POF) [PDF]

Journal of Clinical and Diagnostic Research, 2016
Dyschromatosis Universalis Hereditaria (DUH) belongs to a group of congenital diffuse reticulate pigmentary disorders characterised by both hypo and hyper pigmented macules. It is both hereditary and sporadic.
N.S Jayanthi, V. Anandan, W. Afthab Jameela, V. Senthil Kumar, P. Lavanya   +4 more
doaj   +1 more source

Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

Microorganisms, 2021
ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as ...
Jeanine Rismondo, Lisa Maria Schulz
doaj   +1 more source

Biological Functions and Clinical Significance of the ABCG1 Transporter

Biology
ATP-binding cassette (ABC) transporters are a large family of proteins that transport various substances across cell membranes using energy from ATP hydrolysis.
Stanislav Kotlyarov, Anna Kotlyarova
doaj   +1 more source