Results 61 to 70 of about 156,745 (364)
Biological Functions and Clinical Significance of the ABCG1 Transporter
BiologyATP-binding cassette (ABC) transporters are a large family of proteins that transport various substances across cell membranes using energy from ATP hydrolysis.
Stanislav Kotlyarov, Anna Kotlyarova
doaj +1 more source
eLife, 2014 Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the
Smriti Mishra +5 more
doaj +1 more source
Robust Vision Using Retro Reflective Markers for Remote Handling in ITER [PDF]
Fusion Engineering and Design, Volume 161, 2020, 112080, ISSN
0920-3796, 2020 ITER's working environment is characterized by extreme conditions, that deem maintenance and inspection tasks to be carried out through remote handling. 3D Node is a hardware/software module that extracts critical information from the remote environment during fine alignment tasks using an eye-in-hand camera system and updates the models behind the ...
arxiv +1 more source
Structure and function of the bacterial heterodimeric ABC transporter CydDC: stimulation of ATPase activity by thiol and heme compounds. [PDF]
, 2014 In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ATP-binding cassette-type cysteine/GSH transporter, CydDC.
Baldwin, SA +9 more
core +3 more sources
Mechanistic diversity in ATP-binding cassette (ABC) transporters [PDF]
Nature Structural & Molecular Biology, 2016 Nature Structural & Molecular Biology, 23 (6)
openaire +4 more sources
Multidrug resistance of tumor cells: some new trends in research
Успехи молекулярной онкологии, 2015 Multidrug resistance (MDR) of tumor cells is the resistance to a broad spectrum of structurally unrelated cytotoxic drugs with different mechanisms of action.
A. A. Stavrovskaya, G. P. Guens
doaj +1 more source
Characteristics of transposable element exonization within human and mouse [PDF]
PLoS ONE 5(6):e10907 2010, 2010 Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced cassette exons, an event called exonization. Elucidation of the evolutionary constraints that have shaped fixation of
arxiv +1 more source
The ABCC6 transporter : what lessons can be learnt from other ATP-binding cassette transporters? [PDF]
, 2013 ABC transporters represent a large family of ATP-driven transmembrane transporters involved in uni- or bidirectional transfer of a large variety of substrates.
De Paepe, Anne +2 more
core +2 more sources
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source