Journal of Biological Chemistry, 2002 ATP-binding cassette transporter (ABC) A1 was increased by apolipoprotein A-I without an increase of its message in THP-1 cells. The pulse label study demonstrated that apoA-I retarded degradation of ABCA1.
R. Arakawa, S. Yokoyama
semanticscholar +1 more source
Learning from each other: ABC transporter regulation by protein phosphorylation in plant and mammalian systems [PDF]
, 2015 The ABC (ATP-binding cassette) transporter family in higher plants is highly expanded compared with those of mammalians. Moreover, some members of the plant ABCB subfamily display very high substrate specificity compared with their mammalian ...
Aryal, Bibek +2 more
core +1 more source
Journal of Lipid Research, 2004 Possible mechanisms for the cholesterol-lowering effects of plant stanol esters were addressed by feeding hamsters diets containing stanol esters, cholesterol, or cholestyramine/lovastatin.
F. Jeffrey Field +2 more
doaj +1 more source
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. [PDF]
Biochim Biophys Acta, 2010 ATP-binding cassette transporter A1 - ABCA1, is the most extensively studied transporter in human pathology. ABCA1 became a primary subject of research in many academic and pharmaceutical laboratories immediately after the discovery that mutations at the gene locus cause severe familial High Density Lipoprotein (HDL) deficiency and, in the homozygous ...
Koldamova R, Fitz NF, Lefterov I.
europepmc +4 more sources
Dietary fat and carbohydrate modulate the effect of the ATP-binding cassette A1 (ABCA1) R230C variant on metabolic risk parameters in premenopausal women from the Genetics of Atherosclerotic Disease (GEA) Study [PDF]
, 2015 Table S1. Demographic characteristics of the population. Table S2. Comparison of biochemical parameters stratified by gender and menopausal status. Table 3.
Aida Medina-Urrutia +10 more
core +2 more sources
A novel enzyme immunoassay specific for ABCA1 protein quantification in human tissues and cells
Journal of Lipid Research, 2008 ATP-binding cassette transporter A1 (ABCA1) mediates the transport of cholesterol and phospholipids from cells to lipid-poor HDL and maintains cellular lipid homeostasis.
Vijay Paul +4 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: Accumulating evidence demonstrates that perivascular adipose tissue (PVAT) plays an important role in maintaining vascular homeostasis. The formation of macrophage foam cells is a central feature of atherosclerosis.
Yan Liu +12 more
doaj +1 more source
Phosphorylation and Stabilization of ATP Binding Cassette Transporter A1 by Synthetic Amphiphilic Helical Peptides [PDF]
Journal of Biological Chemistry, 2004 To investigate structural requirement of helical apolipoprotein to phosphorylate and stabilize ATP-binding cassette transporter A1 (ABCA1), synthetic peptides (Remaley, A. T., Thomas, F., Stonik, J. A., Demosky, S. J., Bark, S. E., Neufeld, E. B., Bocharov, A. V., Vishnyakova, T. G., Patterson, A. P., Eggerman, T.
Reijiro Arakawa +5 more
openalex +4 more sources
High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]
, 2018 Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita +8 more
core +2 more sources
Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells
Journal of Lipid Research, 2003 Adipose cells specialized in energy storage, contain large intracellular triglyceride-rich lipid droplets, are enriched with free cholesterol, and express sterol-regulated transcription factors such as liver X receptor (LXR). The recent identification of
Soazig Le Lay +5 more
doaj +1 more source