Results 21 to 30 of about 30,215 (258)

ATP-Citrate Lyase Supports Cardiac Function and NAD⁺/NADH Balance and Is Depressed in Human Failing Myocardium. [PDF]

JACC Basic Transl Sci
Meddeb M, Koleini N, Keykhaei M, Liu T, Rhodehamel M, Mandarano L, Farshidfar F, Zhao L, Kwon S, Keceli G, Ahmet I, Paolocci N, Hahn V, Sharma K, Pearce EL, Kass DA.   +15 more
europepmc   +2 more sources

Publisher Correction: ATP-citrate lyase promotes axonal transport across species [PDF]

Nature Communications, 2021
Aviel Even, Giovanni Morelli, Silvia Turchetto, Michal Shilian, Romain Le Bail, Sophie Laguesse, Nathalie Krusy, Ariel Brisker, Alexander Brandis, Shani Inbar, Alain Chariot, Frédéric Saudou, Paula Dietrich, Ioannis Dragatsis, Bert Brone, Loïc Broix, Jean-Michel Rigo, Miguel Weil, Laurent Nguyen   +18 more
doaj   +2 more sources

ATP-Citrate Lyase in Heart Failure: A Redox Node in NAD⁺/NADH Homeostasis. [PDF]

JACC Basic Transl Sci
Weissman D, Maack C.
europepmc   +3 more sources

Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation. [PDF]

Immunohorizons
Ting KKY, Yu P, Iyayi M, Dow R, Hyduk SJ, Floro E, Ibrahim H, Karim S, Polenz CK, Winer DA, Woo M, Rocheleau J, Jongstra-Bilen J, Cybulsky MI.   +13 more
europepmc   +3 more sources

Hydroxycitrate-loaded exosomes demonstrate enhanced therapeutic efficacy against lung adenocarcinoma by inhibiting the metabolic enzyme ATP citrate lyase. [PDF]

Nanoscale Adv
Phutela K, Bal A, Singh N, Sharma S.
europepmc   +3 more sources

Citrate-Mediated Acyl-CoA Synthesis Is Required for the Promotion of Growth and Triacylglycerol Production in Oleaginous Yeast Lipomyces starkeyi

Microorganisms, 2021
The oleaginous yeast Lipomyces starkeyi is an excellent producer of triacylglycerol (TAG) as a feedstock for biodiesel production. To understand the regulation of TAG synthesis, we attempted to isolate mutants with decreased lipid productivity and ...
Rikako Sato, Satoshi Ara, Harutake Yamazaki, Koji Ishiya, Sachiyo Aburatani, Hiroaki Takaku   +5 more
doaj   +1 more source

From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]

, 2011
Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Adab, P., Blissett, J., Frew, E., Gill, Paramjit, Griffin, T. L., Griffith, L., Hurley, K. L., Jolly, K., Lancashire, E. R., McGee, E., Pallan, M. J., Parry, J. M., Thompson, J. L.   +12 more
core   +13 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Regulation of ATP-citrate lyase gene transcription [PDF]

Yonsei Medical Journal, 1996
It has been suggested that glucose metabolites and insulin are the most important factors inducing ATP-citrate lyase (ACL) by a high carbohydrate diet. We have used a primary culture of rat hepatocytes to confirm the role of glucose and insulin in terms of ACL gene expression.
K S, Kim, J G, Kang, Y A, Moon, S W, Park, Y S, Kim   +4 more
openaire   +3 more sources

ATP-Citrate Lyase Deficiency in the Mouse [PDF]

Journal of Biological Chemistry, 2004
ATP-citrate lyase (Acly) is one of two cytosolic enzymes that synthesize acetyl-coenzyme A (CoA). Because acetyl-CoA is an essential building block for cholesterol and triglycerides, Acly has been considered a therapeutic target for hyperlipidemias and obesity.
Anne P, Beigneux, Cynthia, Kosinski, Bryant, Gavino, Jay D, Horton, William C, Skarnes, Stephen G, Young   +5 more
openaire   +2 more sources