Results 31 to 40 of about 30,215 (258)

The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis [PDF]

open access: yes, 2020
The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids ...
Bucciarelli, Elisabetta   +8 more
core   +1 more source

Depletion of ATP-citrate lyase (ATPCL) affects chromosome integrity without altering histone acetylation in Drosophila mitotic cells [PDF]

open access: yes, 2019
The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A (acetyl-CoA) and oxaloacetate.
CENCI, GIOVANNI   +6 more
core   +2 more sources

The Pathogenetic Basis of the Action of Bempedoic Acid

open access: yesРациональная фармакотерапия в кардиологии, 2023
The modern cardiology has a wide range of medications which affect various pathogenetic links of atherosclerosis, but even the best of them still obtain disadvantages causing intolerance and medicine discontinuation.
A. S. Petrosyan   +4 more
doaj   +1 more source

Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion

open access: yesMolecular Metabolism, 2016
Objective: Glucose-stimulated insulin secretion in pancreatic beta cells requires metabolic signals including the generation of glucose-derived short chain acyl-CoAs in the cytosol from mitochondrially-derived metabolites.
Mahmoud El Azzouny   +5 more
doaj   +1 more source

Minimizing acetate formation in E. coli fermentations [PDF]

open access: yes, 2007
Escherichia coli remains the best established production organisms in industrial biotechnology. However, during aerobic fermentation runs at high growth rates, considerable amounts of acetate are accumulated as by-product.
De Maeseneire, Sofie   +3 more
core   +2 more sources

Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]

open access: yes, 2015
Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel   +2 more
core   +2 more sources

ACLY (ATP citrate lyase) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on ACLY (ATP citrate lyase), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

(-)-Hydroxycitric Acid Reduced Lipid Droplets Accumulation Via Decreasing Acetyl-Coa Supply and Accelerating Energy Metabolism in Cultured Primary Chicken Hepatocytes

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: (-)-Hydroxycitric acid (HCA) had been shown to suppress fat accumulation in animals and humans, while the underlying biochemical mechanism is not fully understood, especially little information is available on whether (-)-HCA regulates ...
Longlong Li   +4 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

open access: yes, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart   +7 more
core   +2 more sources

Unusual Metabolism and Hypervariation in the Genome of a Gracilibacterium (BD1-5) from an Oil-Degrading Community. [PDF]

open access: yes, 2019
The candidate phyla radiation (CPR) comprises a large monophyletic group of bacterial lineages known almost exclusively based on genomes obtained using cultivation-independent methods.
Andersen, Gary L   +7 more
core   +2 more sources

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