Results 61 to 70 of about 30,215 (258)
The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer:Targets for Effective Therapy with 3-Bromopyruvate [PDF]
, 2016 This review summarizes the current state of knowledge about the metabolism of cancer cells, especially with respect to the “Warburg” and “Crabtree” effects.
Lis, Paweł +6 more
core +7 more sources
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation [PDF]
Science, 2009 Chromatin Modifier Modulates Gene Expression Modification of chromatin structure is usually thought of as a global, relatively nonspecific way of modulating gene expression. However, Wellen et al. (p.
Kathryn E, Wellen +5 more
openaire +2 more sources
Advanced Science, EarlyView.In the H‐type electrolytic cell, carbon dioxide is reduced to acetic acid via electro‐microbial catalysis. The simply processed acetic acid is further converted through biological fermentation into high‐value‐added products, including acrylic acid, L‐lactic acid, and β‐alanine.
Kaixing Xiao +8 more
wiley +1 more source
Regulation of protein metabolism in cancer
Molecular & Cellular Oncology, 2018 Our recent studies determined molecular interactions between genes in the ubiquitin-proteasome pathways and cancer cell metabolism. Ubiquitin-specific peptidase 13 (USP13) specifically deubiquitinates and thus upregulates ATP citrate lyase and ...
Cecil Han, Xiongbin Lu, Deepak Nagrath
doaj +1 more source
Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia
Journal of Translational Medicine, 2019 Background Aberrant metabolism is a hallmark of cancer cells. Recently, ATP citrate-lyase (ACLY) expression was demonstrated as an independent predictor of clinical outcome in solid tumors.
Jinghan Wang +7 more
doaj +1 more source
Supplementary Figure 4 from ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms [PDF]
, 2023 Nousheen Zaidi +3 more
openalex +2 more sources
Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]
, 2018 Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J. +14 more
core +3 more sources
International Journal of Cancer, EarlyView.What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan +14 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2016 Efficient redirection of microbial metabolism into the abundant production of desired bioproducts remains non-trivial. Here we used flux-based modeling approaches to improve yields of fatty acids in S. cerevisiae.
Amit Ghosh +9 more
doaj +1 more source