Impacts of Natural and Supplementary Foods on Some Biochemical Activities in the Bodies of Honeybee Workers [PDF]
The experiments were conducted during seasons (summer, au-tumn, winter, and spring) 2020–2021 to study the activities of invertase, adenosine triphosphatase (ATPase), and alkaline phosphatase (AlkP) as well as the determination of total proteins.
Sobhia Sayed+3 more
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Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy [PDF]
The type II AAA+ protein p97 is involved in numerous cellular activities, including endoplasmic reticulum-associated degradation, transcription activation, membrane fusion and cell-cycle control.
Heidi O. Yeung+7 more
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Activation mechanism of the bacterial flagellar dual-fuel protein export engine
Bacteria employ the flagellar type III secretion system (fT3SS) to construct flagellum, which acts as a supramolecular motility machine. The fT3SS of Salmonella enterica serovar Typhimurium is composed of a transmembrane export gate complex and a ...
Tohru Minamino+3 more
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The Use of Fibrinolytic Therapy in Acute Ischemic Events
The loss of tissue perfusion represents the pathological basis underlying acute cerebrovascular events. The occlusion of the brain's blood supply by intravascular thrombotic and/or atherosclerotic phenomena results in a disruption in tissue oxygen and ...
Danny Del Duca
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The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss [PDF]
Mutations in five unconventional myosin genes have been associated with genetic hearing loss (HL). These genes encode the motor proteins myosin IA, IIIA, VI, VIIA and XVA.
Tae-Jun Kwon+13 more
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Expression of a symbiosis-specific gene in Symbiodinium type A1 associated with coral, nudibranch and giant clam larvae [PDF]
Symbiodinium are responsible for the majority of primary production in coral reefs and found in a mutualistic symbiosis with multiple animal phyla. However, little is known about the molecular signals involved in the establishment of this symbiosis and ...
M. Mies+5 more
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Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile [PDF]
DNA replication is an essential and conserved process in all domains of life and may serve as a target for the development of new antimicrobials. However, such developments are hindered by subtle mechanistic differences and limited understanding of DNA ...
Erika van Eijk+8 more
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The vacuolar-type H+-ATPase (V-ATPase) is a multi-subunit proton pump that regulates cellular pH. V-ATPase activity modulates several cellular processes, but cell-type-specific functions remain poorly understood.
Peu Santra, Jeffrey D. Amack
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The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis. [PDF]
The ATPase 6 accessory protein 2 (ATP6AP2)/(pro)renin receptor (PRR) is essential for the biogenesis of active vacuolar H(+)-ATPase (V-ATPase). Genetic deletion of ATP6AP2/PRR causes V-ATPase dysfunction and compromises vesicular acidification.
Kenichiro Kinouchi+12 more
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Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. [PDF]
The P-type ATPase family constitutes a collection of ion pumps that form phosphorylated intermediates during ion transport. One of the best known members of this family is the Na⁺,K⁺-ATPase.
Toru Kimura+4 more
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