Results 21 to 30 of about 615,643 (389)
RNA Interference of Genes Encoding the Vacuolar-ATPase in Liriomyza trifolii
Insects, 2021 The leafminer fly, Liriomyza trifolii, is an invasive pest of vegetable and horticultural crops in China. In this study, a microinjection method based on dsRNA was developed for RNA interference (RNAi) in L. trifolii using genes encoding vacuolar-ATPase (
Ya-Wen Chang +4 more
doaj +1 more source
Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]
, 2020 BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G +4 more
core +2 more sources
SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells
Nature Communications, 2019 Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler SMARCAD1 as a key factor in the control of ERVs in embryonic stem cells ...
Parysatis Sachs +8 more
semanticscholar +1 more source
Probing subunit-subunit interactions in the yeast vacuolar ATPase by peptide arrays. [PDF]
PLoS ONE, 2012 BACKGROUND:Vacuolar (H(+))-ATPase (V-ATPase; V(1)V(o)-ATPase) is a large multisubunit enzyme complex found in the endomembrane system of all eukaryotic cells where its proton pumping action serves to acidify subcellular organelles. In the plasma membrane
Lee S Parsons, Stephan Wilkens
doaj +1 more source
Frontiers in Plant Science, 2023 Vacuolar ATPases (V-ATPases) are proton pumps for proton translocation across membranes that utilize energy derived from ATP hydrolysis; OsV-ATPase subunit d (OsV-ATPase d) is part of an integral, membrane-embedded V0 complex in the V-ATPase complex ...
Qinghua Lu +17 more
doaj +1 more source
Erythrocyte membrane ATPase activity in Sickle cell crisis
Asian Journal of Medical Sciences, 2017 Background: Sickle cell disease is a genetic disease caused by a point mutation in the beta globin gene on chromosome 11 leading to the substitution of valine in place of glutamic acid in beta subunit of globin molecule.
Debapriya Rath
doaj +1 more source
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction [PDF]
, 2019 p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their ...
Long, David T. +3 more
core +1 more source
Frontiers in Plant Science, 2022 V-ATPase is the dominant proton pump in plant cells. It contributes to cytosolic pH homeostasis and energizes transport processes across endomembranes of the secretory pathway. Its localization in the trans Golgi network/early endosomes is essential for vesicle transport, for instance for the delivery of cell wall components. Furthermore, it is crucial
openaire +3 more sources
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding
Science, 2019 Protein unfolding, one substrate at a time Ubiquitin marks proteins for degradation by the proteasome. However, many substrates cannot be directly degraded because they are well folded or are located in cell membranes or in multimeric complexes.
E. C. Twomey +7 more
semanticscholar +1 more source
Molecular basis of mEAK7-mediated human V-ATPase regulation
Nature Communications, 2022 Structural basis of V-ATPase regulation by endogenous proteins is unclear. Here, the authors find mEAK7 as an endogenous V-ATPase modulator and determine its structure with V-ATPase, suggesting the potential role of mEAK7 in V-ATPase regulation.
Rong Wang +3 more
doaj +1 more source