Results 71 to 80 of about 363,756 (199)

Substrate-dependent effects on the conformational equilibrium of the Na +, K +-ATPase monitored by VCF [PDF]

open access: yes, 2009
The Na+,K+-ATPase was discovered more than 50 years ago, but even today the pumpcycle and its partial reactions are still not completely understood.
Geys, Stefan
core  

F-actin reorganization by V-ATPase inhibition in prostate cancer

open access: yesBiology Open, 2017
The vacuolar ATPase (V-ATPase) proton pump sustains cellular pH homeostasis, and its inhibition triggers numerous stress responses. However, the cellular mechanisms involved remain largely elusive in cancer cells.
Yamhilette Licon-Munoz   +3 more
doaj   +1 more source

Na+, K+-ATPase and Ca2+-ATPase activities in the cochlear lateral wall following surgical induction of hydrops.

open access: yes, 2011
Na+,K+-ATPase and Ca2+-ATPase activities have not been studied quantitatively in the cochlea affected by endolymphatic hydrops. The present study was designed to measure quantitatively the Na+,K+-ATPase and Ca2+-ATPase activities in the cochlear lateral ...
SHAU, WEN-YI   +11 more
core  

Control of calcium homeostasis in Schistosoma mansoni

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
Calcium signalling is fundamental for muscular contractility of Schistosoma mansoni. We have previously described the presence of transport ATPases (Na+,K+-ATPase and (Ca2+-Mg2+)-ATPase) and calcium channels (ryanodine receptors - RyR) involved in ...
F Noël   +3 more
doaj   +1 more source

A programmable optical angle clamp for rotary molecular motors [PDF]

open access: yes, 2007
Optical tweezers are widely used for experimental investigation of linear molecular motors. The rates and force dependence of steps in the mechanochemical cycle of linear motors have been probed giving detailed insight into motor mechanisms. With similar
Futai, Masamitsu   +6 more
core   +1 more source

V-ATPase Dysfunction in the Brain: Genetic Insights and Therapeutic Opportunities

open access: yesCells
Vacuolar-type ATPase (v-ATPase) is a multimeric protein complex that regulates H+ transport across membranes and intra-cellular organelle acidification. Catabolic processes, such as endocytic degradation and autophagy, strictly rely on v-ATPase-dependent
Antonio Falace   +5 more
doaj   +1 more source

Investigation of the Proteasome 26S Subunit, ATPase Family Genes as Potential Prognostic Biomarkers and Therapeutic Targets for Hepatocellular Carcinoma

open access: yesCancer Management and Research
Lei Feng,1,* Ning Zhang,1,* Lan Luo,1,* Jie Liu,1,* Yong Yao,1,* Ming-Sheng Gao,1,* Jin Pan,1,* Cai He2 1The Division of Gastroenterology and Hepatology, Suining Central Hospital, Suining City, Sichuan Province, People’s ...
Feng L   +7 more
doaj  

The impact of 3-sulfo-taurolithocholic acid on ATPase activity in patients’ colorectal cancer and normal colon tissues, and its hepatic effects in rodents

open access: yesFrontiers in Veterinary Science
Colorectal cancer is influenced by genetic mutations, lifestyle factors, and diet, particularly high fat intake, which raises bile acid levels in the intestinal lumen.
Solomiia Bychkova   +5 more
doaj   +1 more source

HCO3−-independent pH Regulation in Astrocytes in Situ Is Dominated by V-ATPase

open access: yes, 2015
The mechanisms of HCO3−-independent intracellular pH (pHi) regulation were examined in fibrous astrocytes within isolated neonatal rat optic nerve (RON) and in cultured cortical astrocytes.
R. Fern (7680761)   +3 more
core   +2 more sources

V-ATPase C Acts as a Receptor for Bacillus thuringiensis Cry2Ab and Enhances Cry2Ab Toxicity to Helicoverpa armigera

open access: yesInsects
Cry2Ab is a significant alternative Bacillus thuringiensis (Bt) protein utilized for managing insect resistance to Cry1 toxins and broadening the insecticidal spectrum of crops containing two or more Bt genes. Unfortunately, the identified receptors fail
Pin Li   +7 more
doaj   +1 more source

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