Results 61 to 70 of about 363,756 (199)
针刺研究, 2007 Objective: To compare the effects of electroacupuncture(EA) of "Neiguan" and other acupoints on Na+-K+-ATPase activity and its gene expression in ischemic myocrardial cell membrane in rats.Methods: A total of 50 Wistar rats were randomly divided into ...
YAN Jie +6 more
doaj +2 more sources
Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase
, 2020 Cyclin G-associated kinase (GAK) is a ubiquitous serine/threonine kinase that facilitates clathrin uncoating during vesicle trafficking. GAK phosphorylates a coat adaptor component, AP2M1, to help achieve this function.
Irene Matucci (9291047) +9 more
core
Neural Regeneration ResearchNa+/K+-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na+ out of and two K+ into cells.
Songqiang Huang +3 more
doaj +1 more source
Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy
Molecules, 2017 Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express
Cassiano Felippe Gonçalves-de-Albuquerque +4 more
doaj +1 more source
Involvement of the alpha-subunit N-terminus in the mechanism of the Na+,K+-ATPase
, 2023 Previous studies have shown that cytoplasmic K+ release and the associated E2 → E1 conformational change of the Na+,K+-ATPase is a major rate-determining step of the enzyme's ion pumping cycle and hence a prime site of acute regulatory intervention. From
C. Cranfield (20092251) +5 more
core
Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
Cancer Medicine, 2018 Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H+‐transporter that pumps protons across intracellular and plasma membranes. It consists of a large multi‐subunit protein complex and influences a wide range of cellular processes.
Bradleigh Whitton +3 more
doaj +1 more source
The curious case of vacuolar ATPase: regulation of signaling pathways
Molecular Cancer, 2018 The Vacuolar ATPase (V-ATPase) is a proton pump responsible for controlling the intracellular and extracellular pH of cells. The structure of V-ATPase has been highly conserved among all eukaryotic cells and is involved in diverse functions across ...
Sahithi Pamarthy +3 more
doaj +1 more source
, 2009 The present study was designed to investigate the relationship between the noise-induced temporary threshold shift (TTS) and the specific activities of sodium potassium adenosine triphosphatase (Na+,K+-ATPase) and calcium adenosine triphosphatase (Ca(2 ...
HSU, CHUAN-JEN;CHEN, YUH-SHYANG;SHAU, WEN-YI;YEH, TE-HUEI;LEE, SHIANN-YANN;LIN-SHIAU, SHOEI-YN +1 more
core
Conformational studies of peptides representing a segment of TM7 from Vo-H+-V-ATPase in SDS micelles [PDF]
, 2009 The conformation of a transmembrane peptide, sMTM7, encompassing the cytoplasmic hemi-channel domain of the seventh transmembrane section of subunit a from V-ATPase from Saccharomyces cerevisiae solubilized in SDS solutions was studied by circular ...
Jong, E.R., de +7 more
core +1 more source
The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]
, 2009 The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor +3 more
core +2 more sources