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Lipase Inhibition and Antiobesity Effect of Atractylodes lancea

Planta Medica, 2014
The ethanol extract of Atractylodes lancea rhizome displayed significant lipase inhibition with an IC50 value of 9.06 µg/mL in a human pancreatic lipase assay from high-throughput screening. Bioassay-guided isolation led to the identification of one new polyacetylene, syn-(5E,11E)-3-acetoxy-4-O-(3-methylbutanoyl)-1,5,11-tridecatriene-7,9-diyne-3,4-diol
Ping Jiao
exaly   +3 more sources

Induction and metabolomic analysis of hairy roots of Atractylodes lancea

Applied Microbiology and Biotechnology, 2023
Atractylodes lancea is an important source of traditional Chinese medicines. Sesquiterpenoids are the key active compounds in A. lancea, and their presence determines the quality of the material. Hairy hoot (HR) culture is a potential method to produce medicinally active compounds industrially; however, the induction and metabolic profiling of A ...
Chengcai, Zhang   +6 more
openaire   +2 more sources

Pharmacological research of wild and cultivated Atractylodes lancea

China Journal of Chinese Materia Medica, 2010
To explore the differences of the main pharmacological action in wild and cultivated Atractylodes lancea.Study the effect of the 70% ethanol extracts from the wild and the culticated A. lancea on the mice with gastriculcer induced by absolute ethyl alcohol or HCl.
Donghai, Zhu   +6 more
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Three types of sesquiterpenes from rhizomes of Atractylodes lancea

Phytochemistry, 2008
Eight sesquiterpenes, including four guaiane-types containing an interesting epoxy unit (1-4), a rare tricyclic carbon skeleton-type (5) and three eudesmane-types (6-8), along with five known compounds, were isolated from rhizomes of Atractylodes lancea. The structures and relative configurations of 1-8 were determined by analysis of spectroscopic data,
He-Xiang, Wang   +3 more
openaire   +2 more sources

Determination of tractylodinol in different populations of Atractylodes lancea

China Journal of Chinese Matera Medica, 2010
OBJECTIVE: To establish an RP-HPLC method for determination of atractylodinol in Ateractylodes lancea and compare the contents of atractylodinol in the herbs of different origins. METHOD: The samples were separated on an Agilent TC-C18 (4.6 mm x 250 mm, 5 microm) column with the mobile phase of acetonitrile-water (49:51). Flow rate was 1.0 mL x min(-1).
Chengwu, Fang   +3 more
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Four new sesquiterpenes from Atractylodes lancea

Phytochemistry Letters, 2018
Abstract Four new sesquiterpene compounds, (5R,7R,10S)-3-O-β- d -glucopyranosylisopterocarpolone-11-O-β- d -apiofuranosyl-(1 → 6)-β- d -glucopyranoside (1), (5R,7R,10S)-14-carboxylisopterocarpolone-11-O-β- d -glucopyranoside (2), (1R,7R,10R)-1-hydroxylcarissone-11-O-β- d -glucopyranoside (3), and (1R,7R,10S)-10,11-dihydroxy-4-guaien-3-one 11-O-β- d -
Jian-Shuang Jiang   +4 more
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[The naphtha composing characteristics of geoherbs of Atractylodes lancea].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003
To find the chemical diversity and characteristics of A. lancea on two levels--individuals and populations, and to discover the chemical essentials for forming geoherbs.47 rhizomes of A. lancea were collected in 7 populations, and 6 naphtha components (1. elemol, 2. hinesol, 3. beta-eudesmol, 4. atractylone, 5. atractylodin, 6. atractylenolid I) in the
Lan-ping, Guo   +3 more
openaire   +2 more sources

Diacetoxy-substituted polyacetylenes from Atractylodes lancea

Phytochemistry, 1997
Abstract Six new polyacetylenes have been isolated from the rhizomes of Atractylodes lancea . Besides 1-(2-furyl)-(7 E )-nonene-3,5-diyne-1,2-diacetate, a new natural compound, two further vicinal diacetoxyalkenynes were postulated as erythro- and threo -forms of (1,5 E , 11 E )-tridecatriene-7,9-diyne-3,4-diacetate in comparison with similar ...
Marion S. Lehner   +2 more
openaire   +1 more source

Advances in studies on chemical compositions of Atractylodes lancea and their biological activities

China Journal of Chinese Materia Medica, 2016
This article mainly summarises the results of the chemical compositions and its pharmacological activities of Atractylodes Radix. The chemistry components isolated from Atractylodes Radix are mainly sesquiterpenoids, enediynes, triterpenoids, aromatic glycosides, and etc.
Ai-Ping, Deng   +7 more
openaire   +2 more sources

Six new compounds from Atractylodes lancea and their hepatoprotective activities

Bioorganic & Medicinal Chemistry Letters, 2016
Two new phenolic glycosides with a rare β-d-glucopyranosyl-(1→3)-α-l-rhamnopyranosyl moiety (1, 2), one new dihydrobenzofuran derivative (3), one new pyrazine derivative (4), two new furofuran lignan glycosides (5, 6), and six known compounds (7-12) were isolated from the rhizomes of Atractylodes lancea.
Kuo, Xu   +4 more
openaire   +2 more sources

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