Results 111 to 120 of about 340,736 (281)
Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures
Annals of the Child Neurology Society, EarlyView.ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa +15 more
wiley +1 more source
Sleep Apnoea and AF: Where Do We Stand? Practical Advice for Clinicians
Arrhythmia & Electrophysiology Review, 2021 Suneet Mittal +2 more
doaj +1 more source
Real‐World Edoxaban Concentrations in Older Patients Receiving Reduced‐Dose Regimens
Clinical Pharmacology &Therapeutics, EarlyView.Real‐world edoxaban concentrations in older patients receiving reduced‐dose regimens. Low trough concentrations (< 12 ng/mL) were associated with an increased risk of thromboembolism. Among patients meeting the ELDERCARE‐AF criteria, low drug levels were more frequent with the 15 mg regimen than with the 30 mg regimen.
Sung‐Chun Tang +8 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park +22 more
wiley +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Does atrial fibrillation increase the risk of fractures? A systematic review and meta-analysis
Frontiers in MedicineObjectivesWe have observed in clinical practice that patients with fractures often have concomitant atrial fibrillation. However, it remains unclear whether atrial fibrillation increases the risk of bone fracture.
Wei Chen +9 more
doaj +1 more source
Atrial fibrillation …. more than simply being irregularly irregular [PDF]
, 2014 Gregory Y.H. Lip
openalex +1 more source
Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction
ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu +3 more
wiley +1 more source
Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York
ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta +5 more
wiley +1 more source
The wearable cardioverter-defibrillator is not needed for most high-risk patients
Heart Rhythm O2, 2020 Advay G. Bhatt, MD, FHRS +1 more
doaj +1 more source