Results 51 to 60 of about 98,834 (296)

Slow conduction in the border zones of patchy fibrosis stabilises the drivers for atrial fibrillation: Insights from multi-scale human atrial modelling

Frontiers in Physiology, 2016
Introduction. The genesis of atrial fibrillation (AF) and success of AF ablation therapy have been strongly linked with atrial fibrosis. Increasing evidence suggests that patient-specific distributions of fibrosis may determine the locations of ...
Ross Morgan, Michael Colman, Henry Chubb, Gunnar Seemann, Oleg Aslanidi   +4 more
doaj   +1 more source

The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats

Cardiology Research and Practice, 2021
Objective. This study tends to assess the dose-dependent effects of spironolactone on TGF-β1 expression, atrial fibrosis, and the vulnerability to atrial fibrillation in spontaneously hypertensive rats (SHRs) and tries to clarify the association of ...
Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan   +3 more
doaj   +1 more source

Visualization of intensive atrial inflammation and fibrosis after cryoballoon ablation: PET/MRI and LGE‐MRI analysis

Journal of Arrhythmia, 2021
Background Atrial inflammation plays an important role in initiating atrial fibrosis, which could perpetuate atrial fibrillation (AF). However, the method of visualization of atrial inflammation has not been established.
Kunihiko Kiuchi, Koji Fukuzawa, Munenobu Nogami, Yoshiaki Watanabe, Mitsuru Takami, Yu Izawa, Noriyuki Negi, Katsusuke Kyotani, Shumpei Mori, Ken‐Ichi Hirata   +9 more
doaj   +1 more source

Infrasound exposure promotes development of atrial fibrosis in rats

Annals of Medicine, 2021
Introduction Recent data has shown a significant association between noise exposure and atrial fibrillation (AF) in a large cohort [1] but the pathophysiology remains unclear.
Ana Lousinha, Maria João R. Oliveira, Gonçalo Borrecho, José Brito, Pedro Oliveira, Gonçalo Pereira, António Oliveira de Carvalho, Diamantino Freitas, Artur P. Águas, Eduardo Antunes   +9 more
doaj   +1 more source

Fibrosis and Atrial Fibrillation

JACC: Clinical Electrophysiology, 2017
![Figure][1] In the search for better understanding of atrial fibrillation (AF) mechanisms and the evolution of clinical manifestations of the disease, much recent effort has focused on the role of atrial fibrosis.
openaire   +2 more sources

Cfa-circ002203 was upregulated in rapidly paced atria of dogs and involved in the mechanisms of atrial fibrosis

Frontiers in Cardiovascular Medicine, 2023
Background and aimsThe role of circular RNAs (circRNAs) in the pathophysiology of cardiovascular disease is gradually being elucidated; however, their roles in atrial fibrillation (AF)-related fibrosis are largely unknown.
Wenfeng Shangguan, Tianshu Gu, Rukun Cheng, Xing Liu, Yu Liu, Shuai Miao, Weiding Wang, Fang Song, Hualing Wang, Tong Liu, Xue Liang   +10 more
doaj   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C., Choisy, Stéphanie C., Hancox, Jules C., James, Andrew F., Jones, Sandra A., Kim, Shang-Jin   +5 more
core   +1 more source

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results. [PDF]

, 2015
Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the
Antoons, G, Camm, AJ, Cartlidge, D, Casadei, B, Dobrev, D, EUTRAF investigators, Fabritz, L, Goette, A, Götsche, T, Hatem, S, Jaïs, P, Kirchhof, P, Kockskämper, J, Lendeckel, U, Müller, F-U, Oto, A, Pieske, B, Ravens, U, Rohr, S, Scherr, D, Schotten, U, Steinmeyer, K, Verheule, S   +22 more
core   +3 more sources

New therapeutic target for the non-electrophysiological signaling in atrial fibrosis and fibrillation such as inflammation

Journal of Arrhythmia, 2012
We have experimentally established appropriate models of atrial fibrillation (AF) with atrial interstitial fibrosis. Two approaches were adopted. Firstly, left atrial fibrosis was induced by continuous infusion of angiotensin II (AII).
Naohiko Takahashi, Osamu Kume, Osamu Wakisaka, Yasushi Teshima, Masahide Hara, Tetsunori Saikawa   +5 more
doaj   +1 more source

How to detect atrial fibrosis.

Journal of geriatric cardiology : JGC, 2017
In the last twenty years, new imaging techniques to assess atrial function and to predict the risk of recurrence of atrial fibrillation after treatment have been developed. The present review deals with the role of these techniques in the detection of structural and functional changes of the atrium and diagnosis of atrial remodeling, particularly ...
Lacalzada-Almeida, Juan, García-Niebla, Javier   +1 more
openaire   +2 more sources