Results 31 to 40 of about 65,035 (251)

Atrial fibrillation and cardiac fibrosis

European Heart Journal, 2019
Abstract The understanding of atrial fibrillation (AF) evolved from a sole rhythm disturbance towards the complex concept of a cardiomyopathy based on arrhythmia substrates. There is evidence that atrial fibrosis can be visualized using late gadolinium enhancement cardiac magnetic resonance imaging and that it is a powerful predictor for
Christian Sohns, Nassir F Marrouche
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Atrial fibrosis progression in patients with Atrial Fibrillation [PDF]

Journal of Cardiovascular Magnetic Resonance, 2016
Methods Eighty-eight patients (58% male, mean age 60.4+/-14.7) with AF who underwent late gadolinium enhancement MRI (LGE-MRI) to assess the degree of atrial tissue fibrotic changes were included in this study. All patients underwent at least 2 or more LGE-MRI separated by more than 3 months of follow up.
White, Robert B, Labedi, Mohamed, King, Jordan, Pacchia, Christina F, Johnson, Kara, Kaur, Gagandeep, Cates, Joshua, Morris, Alan, Marrouche, Nassir F   +8 more
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LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation

Molecular Medicine, 2019
Background Long non-coding RNAs (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 in atrial fibrosis remains undefined.
Feng Cao, Zhe Li, Wen-mao Ding, Ling Yan, Qing-yan Zhao   +4 more
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Fibrosis, Myofibroblasts, and Atrial Fibrillation [PDF]

Circulation: Arrhythmia and Electrophysiology, 2015
There can be little doubt about the association between interstitial fibrosis and heart rhythm disturbance. In patients with cardiomyopathy, the extent of myocardial fibrosis has been linked with arrhythmic burden and risk of sudden cardiac death.1 In atrial fibrillation (AF), the relationship between fibrosis and electric dysfunction seems, if ...
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Cadherin-11 Deficiency Attenuates Ang-II-Induced Atrial Fibrosis and Susceptibility to Atrial Fibrillation

Journal of Inflammation Research, 2021
Wei Cao,* Shuai Song,* Guojian Fang,* Yingze Li, Yuepeng Wang, Qun-Shan Wang Department of Cardiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, People’s Republic of China*These ...
Cao W, Song S, Fang G, Li Y, Wang Y, Wang QS   +5 more
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Atrial Fibrosis by Late Gadolinium Enhancement Magnetic Resonance Imaging and Catheter Ablation of Atrial Fibrillation: 5‐Year Follow‐Up Data

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Late gadolinium enhancement magnetic resonance imaging is an effective tool for assessment of atrial fibrosis. The degree of left atrial fibrosis is a good predictor of atrial fibrillation (AF) ablation success at 1 year, but the association ...
Mihail G. Chelu, Jordan B. King, Eugene G. Kholmovski, Junjie Ma, Pim Gal, Qussay Marashly, Mossab A. AlJuaid, Gagandeep Kaur, Michelle A. Silver, Kara A. Johnson, Promporn Suksaranjit, Brent D. Wilson, Frederick T. Han, Arif Elvan, Nassir F. Marrouche   +14 more
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Protein analysis of atrial fibrosis via label-free proteomics in chronic atrial fibrillation patients with mitral valve disease. [PDF]

PLoS ONE, 2013
BACKGROUND: Atrial fibrosis, as a hallmark of atrial structure remodeling, plays an important role in maintenance of chronic atrial fibrillation, but interrelationship of atrial fibrosis and atrial fibrillation is uncertain.
Peide Zhang, Wei Wang, Xin Wang, Xu Wang, Yunhu Song, Yong Han, Jing Zhang, Hui Zhao   +7 more
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LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation

Frontiers in Pharmacology, 2021
Atrial fibrosis is a key contributor to atrial fibrillation (AF). Long non-coding ribonucleic acids (lncRNAs) were demonstrated to exhibit a key role in fibrotic remodeling; however, the function of nuclear-enriched abundant transcript 1 (NEAT1) in ...
Huangdong Dai, Naishi Zhao, Hua Liu, Yue Zheng, Liang Zhao   +4 more
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Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs

International Heart Journal, 2022
Atrial inflammation and fibrosis have long been considered culprits in the development of atrial fibrillation (AF). Prior clinical studies showed that corticosteroid therapy is beneficial in patients with AF. Here we sought to determine whether prednisone treatment prevents atrial tachypacing (ATP) induced atrial fibrosis.Dogs were randomized into the ...
Zhang, He, Lai, Yinchuan, Zhou, Hao, Zou, Lili, Xu, Yanping, Yin, Yuehui   +5 more
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Slow conduction in the border zones of patchy fibrosis stabilises the drivers for atrial fibrillation: Insights from multi-scale human atrial modelling

Frontiers in Physiology, 2016
Introduction. The genesis of atrial fibrillation (AF) and success of AF ablation therapy have been strongly linked with atrial fibrosis. Increasing evidence suggests that patient-specific distributions of fibrosis may determine the locations of ...
Ross Morgan, Michael Colman, Henry Chubb, Gunnar Seemann, Oleg Aslanidi   +4 more
doaj   +1 more source