Results 11 to 20 of about 98,834 (296)

ATRIAL FIBROSIS IS A MORPHOLOGICAL BASIS OF ATRIAL FIBRILLATION

open access: yesРациональная фармакотерапия в кардиологии, 2015
Mechanisms of atrial fibrosis including the role of serotonin in the development of this lesion in patients with atrial fibrillation are presented. New approaches to the treatment of atrial fibrillation aimed at atrial fibrosis reduction are discussed.
O. M. Drapkina, A. V. Emelyanov
doaj   +5 more sources

Myocardial fibrosis and atrial fibrillation

open access: yesРоссийский кардиологический журнал, 2018
Atrial fibrillation is the most prevalent arrhythmia, and tends to progress. Any structural changes in the heart may lead to its progressive remodelling with increased deposition of connective tissue and fibrosis. Predominance of collagen types I and III
S. V. Grigoryan   +2 more
doaj   +3 more sources

Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation

open access: yesJournal of Translational Medicine, 2022
Background Atrial fibrosis plays a critical role in the development of atrial fibrillation (AF). Exosomes are a promising cell-free therapeutic approach for the treatment of AF.
Hongting Hao   +14 more
doaj   +3 more sources

Interactions between atrial fibrosis and inflammation in atrial fibrillation. [PDF]

open access: yesFront Cardiovasc Med
Atrial fibrillation (AF) is a complex arrhythmia driven by intricate pathophysiological mechanisms, with atrial fibrosis and inflammation emerging as central players in its initiation and perpetuation. Key pathways, including the renin-angiotensin-aldosterone system (RAAS), TGF-β/Smad signaling, and pro-inflammatory cytokine cascades (e.g., TNF-α/NF-κB,
Pang Z, Ren Y, Yao Z.
europepmc   +4 more sources

Atrial Fibrillation and Atrial Fibrosis [PDF]

open access: yesJournal of Cardiovascular Pharmacology, 2010
Atrial fibrillation (AF) is the most common arrhythmia in humans. It affects 5% of the population older than age 65 years and is projected to rise as the population ages. Experimental data from animal models of AF show that AF is associated with progressive structural and electrical remodeling of the atria.
Alex Y, Tan, Peter, Zimetbaum
openaire   +2 more sources

Atrial Fibrosis, Ischaemic Stroke and Atrial Fibrillation

open access: yesArrhythmia & Electrophysiology Review, 2021
Atrial fibrosis is an important component of the arrhythmic substrate in AF. Evidence suggests that atrial fibrosis also plays a role in increasing the risk of stroke in patients with the arrhythmia. Patients with embolic stroke of undetermined source (ESUS), who are suspected to have AF but are rarely shown to have it, frequently demonstrate evidence ...
Christian Mahnkopf   +2 more
openaire   +3 more sources

Atrial fibrosis and the mechanisms of atrial fibrillation [PDF]

open access: yesHeart Rhythm, 2007
Atrial fibrillation (AF) is commonly associated with congestive heart failure (CHF), and CHF has been shown to be associated with atrial structural remodeling resulting in fibrosis. Atrial interstitial fibrosis has been seen in patients with CHF and in animal models of pacing-induced heart failure.
Thomas H, Everett, Jeffrey E, Olgin
openaire   +2 more sources

Atrial remodeling, fibrosis, and atrial fibrillation [PDF]

open access: yesTrends in Cardiovascular Medicine, 2015
The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most common arrhythmia seen in clinical practice, are poorly understood, which explains in part why AF prevention and treatment remain suboptimal. Although some clinical parameters have been identified as predicting a transition from paroxysmal to persistent AF in ...
José, Jalife, Kuljeet, Kaur
openaire   +2 more sources

RETRACTED ARTICLE: Anti-fibrotic mechanism of SPP1 knockdown in atrial fibrosis associates with inhibited mitochondrial DNA damage and TGF-β/SREBP2/PCSK9 signaling

open access: yesCell Death Discovery, 2022
Atrial fibrosis occurs frequently with structural heart disease and is considered as a major cause of arrhythmia. Microarray-based profiling predicted the differential expression of SPP1 in atrial fibrosis.
Xianfeng Du   +10 more
doaj   +1 more source

The use of MRI in quantification of the atrial fibrosis in patients with rheumatic mitral disease

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2020
Background Atrial fibrillation (AF) is a common type of arrhythmia with higher incidence in countries with increased prevalence of rheumatic heart disease (RHD), where AF contributes to significant morbidity and mortality in young population.
Ahmed Shehata Ismail   +3 more
doaj   +1 more source

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