Results 11 to 20 of about 65,035 (251)

Assessment of Left Atrial Fibrosis by Cardiac Magnetic Resonance Imaging in Ischemic Stroke Patients Without Atrial Fibrillation: A Systematic Review and Meta‐Analysis [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Left atrial (LA) fibrosis is a marker of atrial cardiomyopathy and has been reported to be associated with both atrial fibrillation and ischemic stroke.
Jin Hean Koh   +10 more
doaj   +2 more sources

Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways. [PDF]

open access: yesPLoS ONE
Atrial fibrillation (AF) represents the commonly occurring cardiac arrhythmia and the main factor leading to stroke and heart failure. Hydrogen (H2) is a gaseous signaling molecule that has the effects of anti-inflammation and antioxidation.
Binmei Zhang   +9 more
doaj   +2 more sources

Involvement of plasminogen activator inhibitor-1 in p300/p53-mediated age-related atrial fibrosis [PDF]

open access: yesPeerJ, 2023
Plasminogen activator inhibitor-1 (PAI-1), a key regulator of the fibrinolytic system, is also intimately involved in the fibrosis. Although PAI-1 may be involved in the occurrence of atrial fibrillation (AF) and thrombosis in the elderly, but whether it
Yingyu Lai   +13 more
doaj   +2 more sources

Sulfur-containing amino acids and their metabolites in atrial fibrosis

open access: yesFrontiers in Pharmacology, 2022
Atrial fibrosis, a symbol of atrial structural remodelling, is a complex process involved in the occurrence and maintenance of atrial fibrillation (AF). Atrial fibrosis is regulated by multiple factors. Sulfur containing amino acids and their metabolites,
Rui Wang   +9 more
doaj   +1 more source

Atrial Fibrillation and Atrial Fibrosis [PDF]

open access: yesJournal of Cardiovascular Pharmacology, 2010
Atrial fibrillation (AF) is the most common arrhythmia in humans. It affects 5% of the population older than age 65 years and is projected to rise as the population ages. Experimental data from animal models of AF show that AF is associated with progressive structural and electrical remodeling of the atria.
Alex Y, Tan, Peter, Zimetbaum
openaire   +2 more sources

Atrial Fibrosis, Ischaemic Stroke and Atrial Fibrillation

open access: yesArrhythmia & Electrophysiology Review, 2021
Atrial fibrosis is an important component of the arrhythmic substrate in AF. Evidence suggests that atrial fibrosis also plays a role in increasing the risk of stroke in patients with the arrhythmia. Patients with embolic stroke of undetermined source (ESUS), who are suspected to have AF but are rarely shown to have it, frequently demonstrate evidence ...
Christian Mahnkopf   +2 more
openaire   +3 more sources

Atrial fibrosis and the mechanisms of atrial fibrillation [PDF]

open access: yesHeart Rhythm, 2007
Atrial fibrillation (AF) is commonly associated with congestive heart failure (CHF), and CHF has been shown to be associated with atrial structural remodeling resulting in fibrosis. Atrial interstitial fibrosis has been seen in patients with CHF and in animal models of pacing-induced heart failure.
Thomas H, Everett, Jeffrey E, Olgin
openaire   +2 more sources

Atrial remodeling, fibrosis, and atrial fibrillation [PDF]

open access: yesTrends in Cardiovascular Medicine, 2015
The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most common arrhythmia seen in clinical practice, are poorly understood, which explains in part why AF prevention and treatment remain suboptimal. Although some clinical parameters have been identified as predicting a transition from paroxysmal to persistent AF in ...
José, Jalife, Kuljeet, Kaur
openaire   +2 more sources

RETRACTED ARTICLE: Anti-fibrotic mechanism of SPP1 knockdown in atrial fibrosis associates with inhibited mitochondrial DNA damage and TGF-β/SREBP2/PCSK9 signaling

open access: yesCell Death Discovery, 2022
Atrial fibrosis occurs frequently with structural heart disease and is considered as a major cause of arrhythmia. Microarray-based profiling predicted the differential expression of SPP1 in atrial fibrosis.
Xianfeng Du   +10 more
doaj   +1 more source

Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice

open access: yesFrontiers in Pharmacology, 2023
As atrial fibrosis is the main feature of atrial structural remodeling, inhibiting atrial fibrosis is crucial to the prevention of atrial fibrillation (AF) progression.
Fangze Huang   +9 more
doaj   +1 more source

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