Results 21 to 30 of about 65,035 (251)

The use of MRI in quantification of the atrial fibrosis in patients with rheumatic mitral disease

The Egyptian Journal of Radiology and Nuclear Medicine, 2020
Background Atrial fibrillation (AF) is a common type of arrhythmia with higher incidence in countries with increased prevalence of rheumatic heart disease (RHD), where AF contributes to significant morbidity and mortality in young population.
Ahmed Shehata Ismail, Yasser Baghdady, Mohammad Ali Salem, Amir Abdel Wahab   +3 more
doaj   +1 more source

Atrial fibrosis underlying atrial fibrillation (Review)

International Journal of Molecular Medicine, 2020
Atrial fibrillation (AF) is one of the most common tachyarrhythmias observed in the clinic and is characterized by structural and electrical remodelling. Atrial fibrosis, an emblem of atrial structural remodelling, is a complex multifactorial and patient‑specific process involved in the occurrence and maintenance of AF.
Li, Chang Yi, Zhang, Jing Rui, Hu, Wan Ning, Li, Song Nan   +3 more
openaire   +3 more sources

Age-related atrial fibrosis [PDF]

AGE, 2008
Many age-related diseases are associated with, and may be promoted by, cardiac fibrosis. Transforming growth factor (TGF)-beta, hypoxia-induced factor (HIF), and the matrix metalloproteinase (MMP) system have been implicated in fibrogenesis. Thus, we investigated whether age is related to these systems and to atrial fibrosis.
Gramley, F, Lorenzen, J, Knackstedt, C, Rana, O, Saygili, E, Frechen, D, Stanzel, S, Pezzella, F, Koellensperger, E, Weiss, C, Münzel, T, Schauerte, P   +11 more
openaire   +3 more sources

Regulation of Atrial Fibrosis by the Bone [PDF]

Hypertension, 2019
MR (mineralocorticoid receptor) antagonists have been demonstrated to provide beneficial effects on preventing atrial fibrosis. However, the underlying cellular and molecular mechanisms remain unclear. We aim to determine the role of osteoblast MR in atrial fibrosis and to explore the underlying mechanism.
Yi, Yi, Lili, Du, Mu, Qin, Xiao-Qing, Chen, Xue-Nan, Sun, Chao, Li, Lin-Juan, Du, Yuan, Liu, Yan, Liu, Jian-Yong, Sun, Zisheng, Tang, Min, Xu, Bing, Fang, Xu, Liu, Sheng-Zhong, Duan   +14 more
openaire   +2 more sources

Progressive and Simultaneous Right and Left Atrial Remodeling Uncovered by a Comprehensive Magnetic Resonance Assessment in Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Left atrial structural remodeling contributes to the arrhythmogenic substrate of atrial fibrillation (AF), but the role of the right atrium (RA) remains unknown.
Clara Gunturiz‐Beltrán, Marta Nuñez‐Garcia, Till F. Althoff, Roger Borràs, Rosa M. Figueras i Ventura, Paz Garre, Gala Caixal, Susanna Prat‐González, Rosario J. Perea, Eva Maria Benito, Jose Maria Tolosana, Elena Arbelo, Ivo Roca‐Luque, Josep Brugada, Marta Sitges, Lluís Mont, Eduard Guasch   +16 more
doaj   +1 more source

LncRNA NRON promotes M2 macrophage polarization and alleviates atrial fibrosis through suppressing exosomal miR-23a derived from atrial myocytes

Journal of the Formosan Medical Association, 2021
Background/purpose: miR-23a is a pro-hypertrophic miRNA that inhibits M2 macrophage polarization. A previous study demonstrated that lncRNA NRON alleviated atrial fibrosis through suppression of M1 macrophages activated by atrial myocytes.
Jianan Li, Qingchun Zhang, Haimiao Jiao
doaj   +1 more source

Atrial Fibrosis in Atrial Fibrillation: Mechanistic Insights, Diagnostic Challenges, and Emerging Therapeutic Targets [PDF]

International Journal of Molecular Sciences
Panagiotis Theofilis, , Antonios Antoniadis   +2 more
exaly   +2 more sources

Apelin Inhibits Angiotensin II-Induced Atrial Fibrosis and Atrial Fibrillation via TGF-β1/Smad2/α-SMA Pathway

Frontiers in Physiology, 2020
BackgroundAngiotensin II (Ang II) could promote the development of atrial fibrosis in atrial fibrillation (AF). Apelin can inhibit the occurrence of myocardial fibrosis.
Wenkui Lv, Wenkui Lv, Ling Zhang, Ling Zhang, Xinchun Cheng, Hongli Wang, Wen Qin, Xianhui Zhou, Xianhui Zhou, Baopeng Tang, Baopeng Tang   +10 more
doaj   +1 more source

Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation [PDF]

European Heart Journal, 2016
Atrial fibrillation (AF) produces a hypercoagulable state. Stimulation of protease-activated receptors by coagulation factors provokes pro-fibrotic, pro-hypertrophic, and pro-inflammatory responses in a variety of tissues. We studied the effects of thrombin on atrial fibroblasts and tested the hypothesis that hypercoagulability contributes to the ...
Spronk, Henri M.H., De Jong, Anne Margreet, Verheule, Sander, De Boer, Hetty C., Maass, Alexander H., Lau, Dennis H., Rienstra, Michiel, van Hunnik, Arne, Kuiper, Marion, Lumeij, Stijn, Zeemering, Stef, Linz, Dominik, Kamphuisen, Pieter Willem, ten Cate, Hugo, Crijns, Harry J., Van Gelder, Isabelle C., van Zonneveld, Anton Jan, Schotten, Ulrich   +17 more
openaire   +3 more sources

Box Isolation of fibrotic areas: A substrate modification approach in atrial fibrillation patients

Revista Portuguesa de Cardiologia, 2017
In the last years, atrial fibrosis was shown to be an independent predictor of procedural failure in patients with paroxysmal and persistent atrial fibrillation.
Fabian Moser, Doreen Schreiber, Andreas Rieger, Monica Trofin, Christian Pönisch, Hans Kottkamp   +5 more
doaj   +1 more source