Results 101 to 110 of about 52,821 (151)

Atrial natriuretic peptide in man

American Journal of Nephrology, 1989
The heart is the major source of atrial natriuretic peptides (ANP). A propeptide is stored in atrial myocytes. In normal humans, atrial distension secondary to volume overload and/or increased atrial pressures are thought to stimulate the secretion of biologically active alpha-ANP (ANF-[99-126], 28 amino residues) into the circulation.
Weidmann P, Saxenhofer H, Ferrier C, Shaw SG   +3 more
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Atrial natriuretic peptide and related peptides

Clinical Chemical Laboratory Medicine, 2007
AbstractIn recent years, biomarkers have been recognized as important tools for diagnosis, risk stratification, and therapeutic decision-making in cardiovascular diseases. Currently, the clinical potential of several natriuretic peptides is under scientific investigation.
Akashi, Yoshihiro J., Springer, Jochen, Lainscak, Mitja, Anker, Stefan D.   +3 more
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HUMAN ATRIAL NATRIURETIC PEPTIDE

Clinical Endocrinology, 1987
Atrial peptides have been the subject of increasing attention since de Bold demonstrated that atrial extracts, when administered to anaethetized rats, induced a potent natriuretic and diuretic response (de Bold, 1979; de Bold et al., 198 1). Within 3 years, specific peptides with natriuretic and vasorelaxant activities were isolated, identified and ...
E A, Espiner, M G, Nicholls
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Atrial natriuretic peptides in man

Canadian Journal of Physiology and Pharmacology, 1987
Research on the physiological role of atrial peptides in man is limited, and the potential for these peptides, or more stable analogues, in therapeutics is uncertain. It is clear, however, that plasma levels of immunoreactive atrial natriuretic peptide (IR-ANP) are increased in volunteers taking a high sodium diet, and are elevated in patients with ...
M G, Nicholls, H, Ikram, I G, Crozier, E A, Espiner, T G, Yandle   +4 more
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Atrial natriuretic peptides in plasma

Clinica Chimica Acta, 2015
Measurement of cardiac natriuretic peptides in plasma has gained a diagnostic role in the assessment of heart failure. Plasma measurement is though hampered by the marked instability of the hormones, which has led to the development of analyses that target N-terminal fragments from the prohormone.
Jens P, Goetze, Lasse H, Hansen, Dijana, Terzic, Nora E, Zois, Jakob, Albrethsen, Annette, Timm, Julie, Smith, Ewa, Soltysinska, Solvej K, Lippert, Ingrid, Hunter   +9 more
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Atrial Natriuretic Peptide in Hypothyroidism*

The Journal of Clinical Endocrinology & Metabolism, 1987
The effect of hypothyroidism on circulating levels of atrial natriuretic peptide (ANP) was studied in 11 hypothyroid patients (aged 11-65 yr; mean, 31 yr) and 13 normal subjects (aged 28-39 yr; mean, 32 yr). Plasma ANP was 32 +/- 9 (+/- SD) pg/ml in normal subjects and 20 +/- 5 pg/ml in the hypothyroid patients (P less than 0.005).
R S, Zimmerman, H, Gharib, D, Zimmerman, D, Heublein, J C, Burnett   +4 more
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Atrial natriuretic peptide stability

Clinical Biochemistry, 2008
Atrial natriuretic peptide (ANP) is a key regulator in the homeostasis of water excretion and has emerged as an important prognostic marker for symptomatic chronic heart failure (CHF). The stability of ANP represents a crucial factor in assessing its use as a cardiac biomarker.
Ronald, Zolty, Carol, Bauer, Pamila, Allen, Maureen, Garrity, Timothy J, Vittorio   +4 more
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Atrial natriuretic peptide and oxidative stress

Peptides, 2010
Atrial natriuretic peptide (ANP) is a hormone, produced mainly by cardiomyocytes, with a major role in cardiovascular homeostatic mechanisms such as natriuresis and vasodilation, which serve to regulate blood pressure. However, ANP also acts as an autocrine/paracrine factor on other targets such as kidney, lung, thymus, liver and the immune system. ANP
DE VITO, PAOLO, Incerpi, S, PEDERSEN, JENS ZACHO, LULY, PAOLO   +3 more
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Platelet aggregation and atrial natriuretic peptide

General Pharmacology: The Vascular System, 1995
1. Isolated human platelets were used to investigate the effect of atrial natriuretic peptide (ANP) on in vitro platelet aggregation induced by epinephrine, ADP, collagen and 5-hydroxytryptamine. As a direct stimulant of particulate guanylate cyclase, ANP is known to have no direct effect on platelets which contain soluble guanylate cyclase. 2.
Ülker S., AkgÜr S., Evinç A., Soykan N., Koşay S.   +4 more
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