Results 31 to 40 of about 738,883 (337)

LGMD D2 TNPO3-Related: From Clinical Spectrum to Pathogenetic Mechanism

Frontiers in Neurology, 2022
Limb-girdle muscular dystrophies (LGMDs) are clinically and genetically heterogeneous diseases presenting with a wide clinical spectrum. Autosomal dominant LGMDs represent about 10–15% of LGMDs and include disorders due to defects of DNAJB6, transportin ...
Roberta Costa, Roberta Costa, Maria Teresa Rodia, Maria Teresa Rodia, Serafina Pacilio, Serafina Pacilio, Corrado Angelini, Giovanna Cenacchi, Giovanna Cenacchi   +8 more
doaj   +1 more source

Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]

, 2019
IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill R, Jack, Clifford R, Jones, David T, Kantarci, Kejal, Knopman, David S, Kremers, Walter K, Lapid, Maria, LEFFTDS Consortium, Lesnick, Timothy G, Rademakers, Rosa, Rosen, Howie, Senjem, Matthew, Syrjanen, Jeremy, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +24 more
core   +2 more sources

Botulinum Toxin Induced Atrophy: An Uncharted Territory

Toxins, 2018
Botulinum neurotoxins (BoNTs) produce local chemo-denervation by cleaving soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) proteins.
Mehri Salari, Soumya Sharma, Mandar S. Jog   +2 more
doaj   +1 more source

The use of mesenchymal stem cells in optic nerve atrophy in patients with multiple sclerosis: A pilot study

Анналы клинической и экспериментальной неврологии, 2017
Introduction. Cellular therapy of multiple sclerosis is currently considered to be one of the most promising treatment alternatives for this severe pathology of the nervous system. Materials and Methods.
Gennadiy N. Bisaga, Anzhelika V. Kovalenko, Galina E. Isaeva, Igor' Yu. Kovalenko, Andrey V. Novitsky, Igor V. Litvinenko   +5 more
doaj   +1 more source

Phenomenological model of diffuse global and regional atrophy using finite-element methods [PDF]

, 2006
The main goal of this work is the generation of ground-truth data for the validation of atrophy measurement techniques, commonly used in the study of neurodegenerative diseases such as dementia.
Camara, O., Cash, D.M., Crum, W.R., Fox, N.C., Hill, D.L.G., Ridgway, G.R., Scahill, R.I., Schnabel, J.A., Schweiger, M., Sneller, B.I.   +9 more
core   +1 more source

Comparison of prefrontal atrophy and episodic memory performance in dysexecutive Alzheimer’s disease and behavioural-variant frontotemporal dementia [PDF]

, 2016
Alzheimer’s disease (AD) sometimes presents with prominent executive dysfunction and associated prefrontal cortex atrophy. The impact of such executive deficits on episodic memory performance as well as their neural correlates in AD, however, remains ...
Alvarez, Ashburner, Bertoux, Bertoux, Binetti, Blennerhassett, Burgess, Chang, de Souza, Delis, Dickerson, Dunn, Fernandez-Calvo, Forman, Frisch, Gilbert, Gleichgerrcht, Gleichgerrcht, Godefroy, Good, Graham, Gregory, Hodges, Hornberger, Hornberger, Hornberger, Irish, Johnson, Kipps, Kopelman, Larner, Liu, Long, McKhann, Meyers, Mez, Mioshi, Mioshi, Moayedi, Morris, Nestor, Nichols, Ossenkoppele, Pa, Pennington, Possin, Rascovsky, Reitan, Rueckert, Savage, Schmidt, Seeley, Smith, Somerville, Swanberg, Torralva, Wedderburn, Wong, Woodward, Woodward, Woodward, Woodward, Zhang, Zheng   +63 more
core   +1 more source

Denervation does not induce muscle atrophy through oxidative stress [PDF]

, 2017
Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Adamo, Sergio, Bellezza, Ilaria, Fulle, Stefania, Greco, Emanuela, Grottelli, Silvia, Mancinelli, Rosa, Minelli, Alba, Moresi, Viviana, Morozzi, Giulio, Pigna, Eva, Rotini, Alessio   +10 more
core   +2 more sources

ON ATROPHY OF THE STOMACH. [PDF]

The Lancet, 1870
n ...
openaire   +3 more sources

Interleukin-17A promotes parietal cell atrophy by inducing apoptosis [PDF]

, 2018
Background & Aims: Atrophic gastritis caused by chronic inflammation in the gastric mucosa leads to the loss of gastric glandular cells, including acid-secreting parietal cells.
Alderuccio, Burclaff, Buzzelli, Caruso, Correa, Correa, Correa, Dai, Degterev, DeLyria, Ding, DiPaolo, DiPaolo, El-Omar, Ferlay, Fox, Ge, Harrington, Hervas-Stubbs, Howlett, Kolls, Landgren, Lennerz, Li, Liao, Machado, McHugh, Merchant, Mills, Moseley, Nam, Nguyen, Nguyen, Nguyen, Nguyen, Onishi, Park, Ramsey, Schumacher, Schwarzenberger, Stummvoll, Varga, Velin, Wada, Yamada, Yamaguchi, Zhang, Zhu   +47 more
core   +3 more sources

ATROPHY OF THE RETINA. [PDF]

JAMA: The Journal of the American Medical Association, 1901
It may be sometimes quite impossible to discover the cause of disease, and it is not always easy to determine whether a lesion is dependent upon some other morbid process, or of primary origin. I have hesitated to believe it possible for atrophy of the retina to come on as a primary condition, without any discoverable preceding inflammation, or even ...
openaire   +3 more sources