Results 31 to 40 of about 768,160 (341)
JAMA: The Journal of the American Medical Association, 1901 It may be sometimes quite impossible to discover the cause of disease, and it is not always easy to determine whether a lesion is dependent upon some other morbid process, or of primary origin. I have hesitated to believe it possible for atrophy of the retina to come on as a primary condition, without any discoverable preceding inflammation, or even ...
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The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]
, 2012 Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
ADNI investigators +5 more
core +1 more source
Orphanet Journal of Rare Diseases, 2011 Abstract Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by degeneration of alpha motor neurons in the spinal cord, resulting in progressive proximal muscle weakness and paralysis. Estimated incidence is 1 in 6,000 to 1 in 10,000 live births and carrier frequency of 1/40-1/60.
D'Amico, Adele +3 more
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Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15
Cell Reports, 2018 Summary: The age-related effects of GDF11 have been a subject of controversy. Here, we find that elevated GDF11 causes signs of cachexia in mice: reduced food intake, body weight, and muscle mass.
Juli E. Jones +10 more
doaj +1 more source
Frontiers in ImmunologyIntroductionBrain atrophy may be a promising marker of relapsing-remitting multiple sclerosis (RRMS) progression, yet it remains underutilized in clinical practice.
Aleksandra Pogoda-Wesołowska +5 more
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Spinal Muscular Atrophy With Myoclonic Epilepsy
Archives of Epilepsy, 2017 Spinal muscular atrophy (SMA) is defined by degeneration of anterior horn cells in the spinal cord. Progressive myoclonic epilepsy (PME) is characterized by myoclonic and generalized seizures with progressive neurological deterioration.
Buket ÖZKARA, Faik BUDAK
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Orphanet Journal of Rare Diseases, 2012 DEFINITION OF THE DISEASE: Dominant Optic Atrophy (DOA) is a neuro-ophthalmic condition characterized by a bilateral degeneration of the optic nerves, causing insidious visual loss, typically starting during the first decade of life. The disease affects primary the retinal ganglion cells (RGC) and their axons forming the optic nerve, which transfer the
Dominique Bonneau +11 more
openaire +6 more sources
BioengineeringFollowing tooth extraction, the bone structure is prone to atrophic changes. Alveolar ridge resorption can compromise subsequent implant treatment not only at the extraction site itself but also by affecting the bone support of adjacent teeth.
Anja Heselich +4 more
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Discussion of Breast Atrophy in One Case
European Journal of Breast Health, 2013 Breast atrophy can occur due to various reasons and it may be a cosmetic problem for women. The main etiological factors are hormonal insufficiency, hormonal axis suppression, virilizing tumors, and the use of anabolic hormones.
Tufan Egeli +3 more
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Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine
Medical Sciences, 2018 Skeletal muscle comprises approximately 40% of the total body mass. Preserving muscle health and function is essential for the entire body in order to counteract chronic diseases such as type II diabetes, cardiovascular diseases, and cancer.
Manuela Cervelli +5 more
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