Results 1 to 10 of about 157,892 (348)

A comparison of myopia control in European children and adolescents with defocus incorporated multiple segments (DIMS) spectacles, atropine, and combined DIMS/atropine.

PLoS ONE, 2023
PurposeTo evaluate the efficacy of a myopia control spectacle lens (DIMS) at slowing the progression of myopia in a population of European children in comparison with 0.01% atropine and combined DIMS and atropine.MethodsThe study was a non-randomised ...
Paolo Nucci, Andrea Lembo, Irene Schiavetti, Rakhee Shah, David Francis Edgar, Bruce John William Evans   +5 more
doaj   +3 more sources

Atropine Differentially Modulates ECM Production by Ocular Fibroblasts, and Its Ocular Surface Toxicity Is Blunted by Colostrum

Biomedicines, 2020
Background: The etiology and the mechanism behind atropine treatment of progressive myopia are still poorly understood. Our study addressed the role of scleral and choroidal fibroblasts in myopia development and atropine function.
Martina Cristaldi, Melania Olivieri, Salvatore Pezzino, Giorgia Spampinato, Gabriella Lupo, Carmelina Daniela Anfuso, Dario Rusciano   +6 more
doaj   +2 more sources

Intraocular Pressure Trends in Children with Myopia Receiving Atropine Therapy [PDF]

Ophthalmology and Therapy
Introduction Topical atropine is widely used for myopia control in children, with proven efficacy in slowing myopia progression. However, concerns remain regarding its potential effects on intraocular pressure (IOP), particularly with long-term use. This
Yun Hsia, Pao-Ju Chen, I-Hsin Ma, Yi-Chieh Lee, Tzu-Hsun Tsai   +4 more
doaj   +2 more sources

Short-Term Effect of Low-Dose Atropine and Hyperopic Defocus on Choroidal Thickness and Axial Length in Young Myopic Adults [PDF]

Journal of Ophthalmology, 2019
Purpose To examine the interaction between a short period of hyperopic defocus and low-dose atropine upon the choroidal thickness and ocular biometrics of healthy myopic subjects.
Beata P. Sander, Michael J. Collins, Scott A. Read   +2 more
openalex   +2 more sources

Systolic hypertension as side effect of topical low dose atropine drops

American Journal of Ophthalmology Case Reports
Purpose: To present a case of increased systemic hypertension and pupil dilation related to low dose atropine eyedrops. Observations: A thirteen-year-old male with progressive myopia received atropine 0.05% ophthalmic drops to slow down myopia ...
Barry N. Wasserman, Erik Massenzio, Karen Lee, David A. Plager   +3 more
doaj   +2 more sources

Efficacy of atropine, orthokeratology, and combined atropine with orthokeratology for childhood myopia: A systematic review and network meta-analysis

Journal of the Formosan Medical Association, 2022
Background/Purpose: Orthokeratology (Ortho-K), atropine eye drops and combined atropine with Ortho-K are proven to be effective ways to prevent myopic progression in many studies, but there is scarce evidence regarding the comparative efficacy of ...
Hou-Ren Tsai, Jen-Hung Wang, Huei-Kai Huang, Tai-Li Chen, Po-Wei Chen, Cheng-Jen Chiu   +5 more
doaj   +1 more source

Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years

JAMA ophthalmology, 2023
This randomized clinical trial investigates if low-dose atropine, 0.01% or 0.02%, slows the progression of myopia in children.
K. Zadnik, Erica Schulman, Ian Flitcroft, J. Fogt, Louis C. Blumenfeld, T. Fong, Eric Lang, H. Hemmati, S. Chandler   +8 more
semanticscholar   +1 more source

The Effect of Low-Dose Atropine on Alpha Ganglion Cell Signaling in the Mouse Retina

Frontiers in Cellular Neuroscience, 2021
Low-dose atropine helps to control myopia progression with few side effects. However, the impact of atropine, a non-selective muscarinic Acetylcholine (ACh) receptor antagonist, on retinal ganglion cells (RGCs) remains unclear. After immersing the cornea
Qin Wang, Seema Banerjee, ChungHim So, ChunTing Qiu, YingHon Sze, Thomas Chuen Lam, Thomas Chuen Lam, Chi-Ho To, Chi-Ho To, Feng Pan, Feng Pan   +10 more
doaj   +1 more source

Low-Dose 0.01% Atropine Eye Drops vs Placebo for Myopia Control: A Randomized Clinical Trial.

JAMA ophthalmology, 2023
Importance Controlling myopia progression is of interest worldwide. Low-dose atropine eye drops have slowed progression in children in East Asia. Objective To compare atropine, 0.01%, eye drops with placebo for slowing myopia progression in US children.
M. Repka, Katherine K. Weise, D. Chandler, Rui Wu, B. Melia, R. Manny, L. A. Kehler, C. Jordan, A. Raghuram, A. Summers, Katherine A. Lee, David B. Petersen, S. Erzurum, Yi Pang, P. Lenhart, B. Ticho, R. Beck, R. Kraker, J. M. Holmes, S. Cotter, Denise D. Alexopoulous, Megan Allen, Heather A Anderson, Darrel Austin, Shane C. Black, N. M. Boyle, Grant Andrew Casey, Moriah A. Chandler, Ryan Chinn, Deborah A. Clausius, B. J. Colon, Courtney L. Conner, Linda T. Curtis, Zainab Dinani, Quayleen Donahue, M. Dubois, Patricia L. Evans, Brooke P. Fimbel, Melanie Kay Fowler, Richard P. Golden, Beth G. Harper, Robert J. Henderson, Dieu-Hong Ho, James E. Hoepner, Kristine B. Hopkins, Ashli S. Jenks, Joseph D. Kaplon, Shabana Khan, Cassandra A Koutnik, Annie F. Kuo, Jessy Lee, Muriel M. Martinez, Sophia Marusic, M. L. McGregor, J. R. McMurtrey, Kathryn B. Miller, Preeti L. Mokka, Jenifer Montejo, Beth A. Morrell, Elyse Nylin, Kimberly C. Odom, Gillaine Ortiz, Samantha A. Parra, Kyle J. Perkins, Larry W. Plum, Ellen Fiona Redenbo, Julianne L. Robinson, Kathleen M. Stutz, Desirae R. Sutherland, Mircea X. Teodorescu, Lori L. Torgensen, D. O. Toro, Phillip B. Turner, Natalie C. Weil, Emily K. Wiecek, C. S. Wilkins, Victoria C. Woodard, Kevin M. Woodruff, Huizi Yin, Marika L. Yumang, Tomohiko Yamada, Noha S. Ekdawi, D. Leske, David K. Wallace, Melanie L. Christian, S. R. Glaser, Eileen E. Birch, Angela M. Chen, Stephen P Christiansen, L. Enyedi, D. Everett, Sharon F. Freedman, William V. Good, Erin C. Jenewein, Richard London, Vivian M Manh, David G. Morrison, S. Pineles, H. Ralay Ranaivo, Tawna L. Roberts, Scott T. Ruark, Bonita R. Schweinler, Jayne L. Silver, D. Suh, L. Verderber, M. Diener‐West, John D. Baker, Barry Davis, Rosemary D. Higgins, Stephen W. Poff, Richard A. Saunders, Lawrence Tychsen   +111 more
semanticscholar   +1 more source

Varying Dose of Atropine in Slowing Myopia Progression in Children Over Different Follow-Up Periods by Meta-Analysis

Frontiers in Medicine, 2022
Purpose: To evaluate the efficacy and safety of atropine for slowing myopia progression and to investigate whether the treatment effect remains constant with continuing treatment.Method: Studies were retrieved from MEDLINE, EMBASE, and the Cochrane ...
Jiahe Gan, Jiahe Gan, Shi-Ming Li, Shi-Ming Li, Shanshan Wu, Kai Cao, Kai Cao, Dandan Ma, Dandan Ma, Xi He, Xi He, Ziyu Hua, Ziyu Hua, Meng-Tian Kang, Meng-Tian Kang, Shifei Wei, Shifei Wei, Weiling Bai, Weiling Bai, Ningli Wang, Ningli Wang   +20 more
doaj   +1 more source