Results 141 to 150 of about 111,342 (315)
THE ACTION OF ATROPINE, BENACTYZINE, AND SCOPOLAMINE UPON FIXED‐INTERVAL AND FIXED‐RATIO BEHAVIOR [PDF]
John J. Boren, Albert P. Navarro
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Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander+5 more
wiley +1 more source
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin+6 more
wiley +1 more source
Co-expression of Gbeta 5 Enhances the Function of Two Ggamma Subunit-like Domain-containing Regulators of G Protein Signaling Proteins [PDF]
Regulators of G protein signaling (RGS) stimulate the GTPase activity of G protein Galpha subunits and probably play additional roles. Some RGS proteins contain a Ggamma subunit-like (GGL) domain, which mediates a specific interaction with Gbeta 5. The
Chen, Ching-Kang+5 more
core
REVERSAL OF NICOTINE ACTION ON THE INTESTINE BY ATROPINE [PDF]
N Ambache, Jennifer M. Edwards
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Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra+4 more
wiley +1 more source
Best practices for blood collection and anaesthesia in mice: Selection, application and reporting
Abstract Blood collection in mice is a common procedure in biomedical research. The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experimental setup, animal welfare considerations and the intended downstream analyses.
Zhixin Li+10 more
wiley +1 more source
A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART [PDF]
A. J. Carlson
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Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia+14 more
wiley +1 more source