Anaesthesia, Volume 81, Issue 6, Page 867-874, June 2026.Summary Introduction Injectable medicines represent a significant proportion of the annual medicines expenditure of the NHS in England, totalling £7 billion ($9.4 billion, €8.0 billion) in 2023. This represents approximately 70% of hospital medicines spending and includes essential treatments delivered at the point of care, such as chemotherapy ...
Suzanne Al‐Rawi +2 more
wiley +1 more source
Fentanyl Compromises Lower‐Airway Mechanics and Naloxone Triggers a Transient Mechanical Overshoot
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the leading cause of death following opioid overdose, due to its effects on central rhythm generation, and airway and thoracic constriction. While the effects on rhythm generation have been well documented, the effects of fentanyl on airway constriction are less well understood. We tested the
Riley R. Parks +4 more
wiley +1 more source
Anticholinergic Medication Burden Scales: A Systematic Review
Journal of the American Geriatrics Society, Volume 74, Issue 6, Page 1771-1784, June 2026.ABSTRACT Background Anticholinergic burden refers to the cumulative anticholinergic effect of all medications taken by an individual. Anticholinergic burden scales help identify patients at risk of anticholinergic adverse effects and guide prescribing. However, substantial variation exists between scales, with no gold standard identified.
Orla Vennard +4 more
wiley +1 more source
Atropine in hypoxic bradycardia
Bradycardia during hypoxic events, such as in “can’t intubate, can’t oxygenate” scenarios, may reflect a protective oxygen-conserving reflex rather than a correctable pathology.
Tomas Parizek
core
Some Worlds about Postmortem Blood Atropine Concentrations
, 2013 which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Atropine is an anticholinergic drug, used in treatment of spasm and pain.
Phak-rop Pos Pok
core
The Journal of Physiology, Volume 604, Issue 12, Page 4945-4967, 15 June 2026.Abstract figure legend Obesity and metabolic syndrome (MetS) are well‐known major risk factors for overactive bladder (OAB). Mechanisms underlying obesity‐/MetS‐associated OAB were explored using a high‐fat‐diet (HFD)‐induced obesity mouse model. HFD‐induced obesity/MetS mice developed an OAB phenotype characterized by enlarged non‐voiding contractions
Ayu Sugiura +3 more
wiley +1 more source
Effectiveness of Low-Dose Atropine for Myopia Control in European Children: A Real-World Cohort Study. [PDF]
J Clin MedAlvarez-Peregrina C +7 more
europepmc +1 more source
Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth. [PDF]
World J Clin PediatrCapobianco M +7 more
europepmc +1 more source
Atropine-induced intraocular pressure changes and anterior segment structural parameters in dogs assessed by ultrasound biomicroscopy. [PDF]
Front Vet SciLee M +6 more
europepmc +1 more source
Navigating the Core Challenges of Atropine Therapy in Myopia: A Mechanistic and Clinical Analysis of Dose, Response, and Durability. [PDF]
J OphthalmolJiang Q, Yang J, Cao X, Mou L.
europepmc +1 more source