Results 31 to 40 of about 114,786 (336)

The Role of Voltage-Gated Sodium Channel 1.8 in the Effect of Atropine on Heart Rate: Evidence From a Retrospective Clinical Study and Mouse Model

open access: yesFrontiers in Pharmacology, 2020
Atropine is commonly used to counter the effects of the parasympathetic neurotransmitter acetylcholine on heart rate in clinical practice, such as in the perioperative period; however, individual differences in the response to atropine are huge.
Baowen Liu   +9 more
doaj   +1 more source

Effect of atropine 0.01% on myopia control in children aged 6–13 years during the 2022 lockdown in Shanghai

open access: yesFrontiers in Public Health, 2023
PurposeTo compare the myopic progression in children treated with 0. 01% atropine and those who discontinued atropine during the 2022-home quarantine in Shanghai.MethodsIn this retrospective study, children aged 6–13 years with follow-up visits before ...
Manrong Yu   +8 more
doaj   +1 more source

Current trends among pediatric ophthalmologists to decrease myopia progression—an international perspective [PDF]

open access: yes, 2018
Purpose To explore what the current worldwide preferred practice patterns of pediatric ophthalmologists are to decrease myopia progression among their patients.
Farzavandi, Sonal K.   +5 more
core   +1 more source

High‐concentration atropine induces corneal epithelial cell apoptosis via miR‐30c‐1/SOCS3

open access: yesKaohsiung Journal of Medical Sciences, 2022
Atropine is an anticholinergic drug widely used in the field of ophthalmology, but its abuse can cause cytotoxicity to the cornea, resulting in blurred vision.
Xi‐Jia Chen, Po Hu, Shu Yi
doaj   +1 more source

Efficacy of atropine, orthokeratology, and combined atropine with orthokeratology for childhood myopia: A systematic review and network meta-analysis

open access: yesJournal of the Formosan Medical Association, 2022
Background/Purpose: Orthokeratology (Ortho-K), atropine eye drops and combined atropine with Ortho-K are proven to be effective ways to prevent myopic progression in many studies, but there is scarce evidence regarding the comparative efficacy of ...
Hou-Ren Tsai   +5 more
doaj  

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

open access: yes, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma   +3 more
core   +1 more source

The Invalidity of the Laplace Law for Biological Vessels and of Estimating Elastic Modulus from Total Stress vs. Strain: a New Practical Method [PDF]

open access: yes, 2013
The quantification of the stiffness of tubular biological structures is often obtained, both in vivo and in vitro, as the slope of total transmural hoop stress plotted against hoop strain. Total hoop stress is typically estimated using the "Laplace law."
Brasseur, James G., Costanzo, Francesco
core   +1 more source

Cholinergic suppression: A postsynaptic mechanism of long-term associative learning [PDF]

open access: yes, 1986
Food avoidance learning in the mollusc Pleurobranchaea entails reduction in the responsiveness of key brain interneurons in the feeding neural circuitry, the paracerebral feeding command interneurons (PCNs), to the neurotransmitter acetylcholine (AcCho).
Davis, W. Jackson   +5 more
core   +2 more sources

Neuroprotective Effects of Antidotes in Soman-Poisoned Rats

open access: yesActa Medica, 1999
1. The neuroprotective effects of antidotes (atropine, obidoxime/atropine mixture, HI-6/atropine mixture) on rats poisoned with soman at a sublethal dose (48 μg/kg i.m.; 60% of LD50 value) were studied.
Jiří Kassa, Marie Koupilová
doaj   +1 more source

Low-dose AtropIne for Myopia Control in Children (AIM): protocol for a randomised, controlled, double-blind, multicentre, clinical trial with two parallel arms

open access: yesBMJ Open, 2023
Introduction Myopia is a major cause of degenerative eye disease and increases the risk of secondary visual impairment. Mitigating its progression therefore has great potential of clinically relevant benefit as shown by using highly diluted atropine eye ...
Armin Wolf   +26 more
doaj   +1 more source

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