Results 71 to 80 of about 157,892 (348)

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Usefulness of serum lactate as a predictor of successful discontinuation of continuous atropine infusion in patients with severe acute organophosphate poisoning [PDF]

Clinical and Experimental Emergency Medicine, 2018
Objective In severe organophosphate (OP) poisoning, administration of atropine via continuous intravenous infusion is typically considered. To date, there have been no studies on predicting successful atropine discontinuation through plasma ...
Ho Chul Kwon, Yong Sung Cha, Gyo Jin An, Yoonsuk Lee, Hyun Kim   +4 more
doaj   +1 more source

Novel Insights Into the Bioactive Profile and Therapeutic Potentials of Indonesian Annona muricata Leaves

Chemistry &Biodiversity, EarlyView.
Pharmacological investigation of the aqueous extract of Annona muricata L. leaves from Indonesia. ABSTRACT This study investigates, for the first time, the comprehensive pharmacological profile of the aqueous extract of Annona muricata L. (graviola) leaves from Indonesia, focusing on its antioxidant, antinociceptive, and anti‐inflammatory properties ...
Sara Oufquir, Fatimazahra Agouram, Hamid Kabdy, Mehdi Ait Laaradia, Khadija Oubella, Baslam Abdelmoniim, Aboufatima Rachida, Stefania Garzoli, Abderrahman Chait   +8 more
wiley   +1 more source

Atropine injection followed by coronary artery spasm with ventricular tachycardia during spinal anesthesia -A case report- [PDF]

Korean Journal of Anesthesiology, 2013
Bradycardia may occur during spinal anesthesia with atropine commonly used as a treatment. A 44-year-old female with no known history of any underlying diseases, developed a coronary spasm following ventricular tachycardia when 0.5 mg of atropine was ...
Joon-Ho Lee, Ji-Hye Seok, Young-Lok Kim, Ji-Hyang Lee, Sang-Gon Lee, Eun-Ju Kim, Da-Mi Seo   +6 more
doaj   +1 more source

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed, Al-Abed, Yousef, Coleman, Thomas, Lakshminrusimha, Satyanarayana, Patel, Hardik, VanPatten, Sonya   +5 more
core   +2 more sources

Additive effect of atropine eye drops and short-term retinal defocus on choroidal thickness in children with myopia

Scientific Reports, 2020
Atropine eye drops and myopic retinal defocus each slow progression of myopia (short-sight). They also cause thickening of the choroid, and it has been suggested that the thickening is a precursor for reduced eye growth and slowed myopia progression.
S. Chiang, Philip R. K. Turnbull, J. Phillips   +2 more
semanticscholar   +1 more source

Endothelium‐Independent Relaxation of Alkaloid Boldine in Isolated Aortas From Normotensive and Hypertensive Rats: Participation of Ca2+ Channels

Chemistry &Biodiversity, EarlyView.
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo, Rita de Cássia Vilhena da Silva, Valdir Cechinel Filho, Priscila de Souza   +3 more
wiley   +1 more source

Retardation of myopia by atropine regimes [PDF]

International Journal of Ophthalmology
Myopia is a huge health problem due to its high frequency, vision losses and public health cost. According to the World Health Organization, at least 2.2 billion people have vision impairment.
Qin Zhu, Li Chen, Jia-Rui Liang, Min Hu, Li-Ping Xue, Guang-Long Zhou, Yuan Zhou, Jie-Ying Zhang, David Fernandez-Hazoury, Allison Helman, Ying-Ting Zhu, Xiao-Fan Zhang   +11 more
doaj   +1 more source

Evaluating the Effect of Topical Atropine Use for Myopia Control on Intraocular Pressure by Using Machine Learning

Journal of Clinical Medicine, 2020
Atropine is a common treatment used in children with myopia. However, it probably affects intraocular pressure (IOP) under some conditions. Our research aims to analyze clinical data by using machine learning models to evaluate the effect of 19 important
Tzu‐En Wu, Hsin-An Chen, Mao-Jhen Jhou, Yen-Ning Chen, Tingjen Chang, Chi-Jie Lu   +5 more
semanticscholar   +1 more source

Opioid and Nitrergic Pathways Mediate Antinociception by Pectis elongata Kunth. Essential Oil

Chemistry &Biodiversity, EarlyView.
ABSTRACT In the present study, we aimed to evaluate the antinociceptive potential of the Pectis elongata essential oil (PeEO) and to understand its mechanism of action by identifying possible pain inhibition pathways. PeEO was analyzed using gas chromatography coupled with mass spectrometry.
Angela Palma Amorin, Sandra Layse Ferreira Sarrazin, Leomara Andrade da Silva, Thaiana Neves Coelho, Adriele Pantoja Cunha, Vitória Albuquerque de Lima, Domingas Machado da Silva, Pablo Luis Baia Figueiredo, Ricardo Bezerra de Oliveira   +8 more
wiley   +1 more source