Boreas, EarlyView.The site of Barmaky currently marks the oldest Epigravettian occupation of north‐western Ukraine shortly after the Last Glacial Maximum (LGM), dated to around 19 cal. ka BP. Stable isotope analyses of bone collagen from six terrestrial mammals and two bird species show a comparatively highly structured palaeo‐food web.
Lilian Reiss +6 more
wiley +1 more source
Perspective of the Pharmaceuticals and Medical Devices Agency on Drug Development for Childhood Myopia. [PDF]
Clin Pharmacol TherPathologic myopia represents a global public health concern, with increasing prevalence and vision loss risk. Myopia typically develops in childhood and progresses more rapidly with earlier onset. Clinical trials exploring treatments for decelerating myopia progression are underway.
Arima M +9 more
europepmc +2 more sources
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Evaluation of intravenous lipid emulsion as a novel therapeutic antidote in severe organophosphorous poisoning- A prospective randomized, comparative study [PDF]
Al Ameen Journal of Medical Sciences, 2019 Background: Organophosphorus compounds are usually esters, amides or thiol derivatives of phosphonic acid and form a large family (>50000 compounds). The principal use of these compounds are as pesticides in agriculture, mainly as insecticides.
Shabnum Majeed, Altaf H. Malik, B.A. Dar
doaj
PLoS ONE, 2018 A study has been made of the effect of chronic exercise on myocardial electrophysiological heterogeneity and stability, as well as of the role of cholinergic neurons in these changes.
Luis Such-Miquel +11 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Mavacamten (MAVA) is a novel small molecule inhibitor of cardiac myosin, mitigating cardiomyocyte hypercontractility in patients with hypertrophic obstructive cardiomyopathy (HOCM). Despite its recent approval for clinical use, the transcriptional and functional impacts of MAVA remain not well understood.
Elisa Kiselev +36 more
wiley +1 more source
Open-Label Randomized Clinical Trial of Atropine Bolus Injection Versus Incremental Boluses Plus Infusion for Organophosphate Poisoning in Bangladesh [PDF]
, 2012 Mohammed Joynal Abedin +5 more
openalex +1 more source
Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse
Equine Veterinary Education, EarlyView.Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx +5 more
wiley +1 more source
Dobutamine-Atropine Stress Echocardiography for the Detection of Coronary Artery Disease in Patients With Left Ventricular Hypertrophy [PDF]
, 2000 Steven C. Smart +3 more
openalex +1 more source
Successful repair of a carpal sheath synovial hernia using a polypropylene mesh
Equine Veterinary Education, EarlyView.Summary A cob‐cross mare presented with a carpal sheath synovial hernia on the distolateral antebrachium following carpal sheath tenoscopy to treat a radial physeal exostosis and deep digital flexor tendon injury. The presumed source of pain was the weakened skin over the hernia as the intrathecal pathology identified at the initial tenoscopy had ...
S. R. L. Neild +3 more
wiley +1 more source