Results 41 to 50 of about 93,133 (242)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Attachment Theory and Concepts of God
SAGE Open, 2014 We replicated and extended Buri and Mueller’s study, which tested whether one’s God concept is primarily self- or parent-referenced. Following their findings, we predicted that God concepts would primarily be self-referenced.
Duane F. Reinert, Carla E. Edwards
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Parenting and children's representation of interpersonal relations: foreign research review [PDF]
Современная зарубежная психология, 2017 The article provides an overview of the Western empirical research dealing with various types of individual internal representations, emerging and/or functioning in the child-parent relationship.
Yaroshevskaya S.V.
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Close relationships in Parkinson´s disease patients with device‐aided therapy
Brain and Behavior, 2021 Objectives Deep brain stimulation, continuous subcutaneous apomorphine infusion, and levodopa–carbidopa intestinal gel infusion, together called device‐aided therapies (DAT), are introduced when oral and transdermal pharmacotherapy are not enough for a ...
Monica Scharfenort +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Gaya Kelekatan Remaja dan Orang Tua pada Siswa SMP Negeri 1 Nguter Kabupaten Sukoharjo
Indonesian Journal of Guidance and Counseling: Theory and Application, 2017 Attachment theory adolescents and parents can be a shield for adolescents to avoid delinquency, so this study wanted to know what type of attachment that occurs between adolescents and parents.
Latih Buran Tedra
doaj
Malaysian Journal of Learning and Instruction, 2017 Purpose – Building upon attachment theory and emerging theory, the current study was aimed at examining the effect of peer attachment in predicting adjustment to life in university among freshmen in a public unirvsity in East Malaysia.
Walton Wider +3 more
doaj +1 more source