Results 21 to 30 of about 368,625 (356)

Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 192, Issue 1-2, Page 3-12, January-March 2023., 2023
Abstract Ubiquitous associations have been detected between different types of childhood psychopathology and polygenic risk scores based on adult psychiatric disorders and related adult outcomes, indicating that genetic factors partly explain the association between childhood psychopathology and adult outcomes. However, these analyses in general do not
Wonuola A. Akingbuwa, Anke R. Hammerschlag, Andrea G. Allegrini, Hannah Sallis, Ralf Kuja‐Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R. Munafò, Robert Plomin, Michel G. Nivard, Meike Bartels, Christel M. Middeldorp   +12 more
wiley   +1 more source

Neural Correlates of Duration Discrimination in Young Adults with Autism Spectrum Disorder, Attention-Deficit/Hyperactivity Disorder and Their Comorbid Presentation

Frontiers in Psychiatry, 2018
Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often co-occur and share neurocognitive deficits. One such shared impairment is in duration discrimination. However, no studies using functional magnetic resonance imaging
Steve D. Lukito, Owen G. O'Daly, David J. Lythgoe, Susannah Whitwell, Amanda Debnam, Clodagh M. Murphy, Clodagh M. Murphy, Clodagh M. Murphy, Karen Ashwood, Karen Ashwood, Karen Ashwood, Vladimira Stoencheva, Vladimira Stoencheva, Vladimira Stoencheva, Emily Simonoff, Katya Rubia   +15 more
doaj   +1 more source

Vitamin D Status at Birth and Future Risk of Attention Deficit/Hyperactivity Disorder (ADHD). [PDF]

PLoS ONE, 2015
To investigate whether children with Attention Deficit/Hyperactivity Disorder have lower levels of Vitamin D3 at birth than matched controls.Umbilical cord blood samples collected at birth from 202 children later diagnosed with Attention Deficit ...
Peik Gustafsson, Lars Rylander, Christian H Lindh, Bo A G Jönsson, Amanda Ode, Per Olofsson, Sten A Ivarsson, Anna Rignell-Hydbom, Nils Haglund, Karin Källén   +9 more
doaj   +1 more source

Sluggish cognitive tempo symptoms cooccurring with attention deficit hyperactivity disorder

Middle East Current Psychiatry, 2023
Background In the current study, the main aim was investigating the sociodemographic features and sluggish cognitive tempo symptoms of children diagnosed with attention deficit hyperactivity disorder and followed at an attention deficit hyperactivity ...
Merve Cikili Uytun, Esra Yurumez, Tugba Mentese Babayigit, Gokce Yagmur Efendi, Birim Gunay Kilic, Didem Behice Oztop   +5 more
doaj   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

The transition from children’s services to adult services for young people with attention deficit hyperactivity disorder: the CATCh-uS mixed-methods study

Health Services and Delivery Research, 2020
Background: Attention deficit hyperactivity disorder was previously seen as a childhood developmental disorder, so adult mental health services were not set up to support attention deficit hyperactivity disorder patients who became too old for child ...
Astrid Janssens, Helen Eke, Anna Price, Tamsin Newlove-Delgado, Sharon Blake, Cornelius Ani, Philip Asherson, Bryony Beresford, Tobit Emmens, Chris Hollis, Stuart Logan, Moli Paul, Kapil Sayal, Susan Young, Tamsin Ford   +14 more
doaj   +1 more source

EEG for Diagnosis of Adult ADHD: A Systematic Review With Narrative Analysis

Frontiers in Psychiatry, 2020
BackgroundAttention deficit hyperactivity disorder is a common neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity and or impulsivity.
Marios Adamou, Tim Fullen, Sarah L. Jones   +2 more
doaj   +1 more source

Automatic diagnosis of schizophrenia and attention deficit hyperactivity disorder in rs-fMRI modality using convolutional autoencoder model and interval type-2 fuzzy regression [PDF]

, 2022
Nowadays, many people worldwide suffer from brain disorders, and their health is in danger. So far, numerous methods have been proposed for the diagnosis of Schizophrenia (SZ) and attention deficit hyperactivity disorder (ADHD), among which functional magnetic resonance imaging (fMRI) modalities are known as a popular method among physicians.
arxiv   +1 more source

SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism

Archiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
ZEL‐H16 (1) has been disclosed to be a high‐affinity non‐imidazole H3R (partial) agonist. However, it was found that 1 acts as an inverse agonist for Gαi in various assays. Concise structure–activity relationship studies, molecular pharmacology, and docking were used to shed more light on the properties of 1.
Gábor Wágner, Tamara A. M. Mocking, Xiaoyuan Ma, Inna Slynko, Daniel Da Costa Pereira, Robin Breeuwer, Niek J. N. Rood, Cas van der Horst, Henry F. Vischer, Chris de Graaf, Iwan J. P. de Esch, Maikel Wijtmans, Rob Leurs   +12 more
wiley   +1 more source

Measures of tonic and phasic activity of the locus coeruleus—norepinephrine system in children with autism spectrum disorder: An event‐related potential and pupillometry study

Autism Research, Volume 15, Issue 12, Page 2250-2264, December 2022., 2022
Abstract A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event‐related potential [ERP]) indices may provide meaningful ...
Yesol Kim, Girija Kadlaskar, Rebecca McNally Keehn, Brandon Keehn   +3 more
wiley   +1 more source